Research Progress in Animal Models of Bone Defects

doi:10.13701/j.cnki.kqyxyj.2021.09.003

Abstract

Abstract: After the bone defect reaches a certain range and distance, the body cannot repair itself, that is, the critical bone defect, which requires autogenous bone transplantation, allogeneic bone transplantation or bone tissue engineering to repair. Animal models of bone defects are often used to evaluate the regeneration capacity of bone substitute biomaterials in bone tissue engineering. This article summarizes the animal bone defect models commonly used in recent years and their current research directions, and focuses on oral animal bone defect models.

Key words: bone defect, animal model, bone substitute biomaterial, regeneration, critical bone defect

LU Jiarui, QUAN Jingjing. Research Progress in Animal Models of Bone Defects[J]. Journal of Oral Science Research, 2021, 37(9): 783-786.

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