Journal of Oral Science Research ›› 2020, Vol. 36 ›› Issue (9): 808-810.DOI: 10.13701/j.cnki.kqyxyj.2020.09.002

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Research Progress of PRF in Periodontal Regeneration

SUN Tao, HE Hongbing*   

  1. Department of Periodontics, the Affiliated Hospital of Stomatology of Kunming Medical University, Kunming 650106, China
  • Received:2019-10-21 Online:2020-09-28 Published:2020-09-15

Abstract: Periodontal tissue regeneration is always a difficult and hot point in the treatment of periodontitis. PRF is a second-generation autologous platelet plasma product containing cells, growth factors, and fibrin biological scaffolds. In recent years, the physical and chemical properties of PRF have changed due to LSCC guided preparation procedure, and some new branches have been formed. PRF is close to the ideal microenvironment system of tissue regeneration in terms of biological signaling molecules, biological scaffolds, and blood supply, which can promote the revascularization and tissue healing. PRF can be used in combination with drugs and cells to promote the occurrence of periodontal tissue regeneration. This paper will review the researches of PRF in periodontal tissue regeneration in recent years.

Key words: platelet-rich fibrin, periodontal regeneration, revascularization