Journal of Oral Science Research ›› 2019, Vol. 35 ›› Issue (11): 1016-1019.DOI: 10.13701/j.cnki.kqyxyj.2019.11.002

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Recent Advancement in Development and Regeneration of Exosomes in Oral Tissues

SHI Weiwei1,2, GUO Shujuan1,2*   

  1. 1.State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China;
    2. Department of Periodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2018-12-24 Online:2019-11-28 Published:2019-11-21

Abstract: Exosomes secreted by cells are small vesicles. As a nanoscale signal molecule, exosomes play a key role in the communication among cells, tissue, and organs. Recently, studies demonstrate that exosomes can promote angiogenesis, wound healing, and bone regeneration. This paper reviewed relevant studies about the effect of exosomes on promting the organogenesis and regeneration of oral tissue.

Key words: exosomes, oral tissue development, stem cell, dental pulp regeneration, periodontal regeneration