Journal of Oral Science Research ›› 2021, Vol. 37 ›› Issue (9): 787-790.DOI: 10.13701/j.cnki.kqyxyj.2021.09.004

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Research Progress on Osteoimmunology Properties of β-TCP

SHAN Yuhua, CHEN Zhenqi*   

  1. Department of Orthodontics, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Oral Disease; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai 200011, China
  • Received:2020-04-08 Online:2021-09-28 Published:2021-09-16

Abstract: β-tricalcium phosphate (β-TCP), as bone graft material, has excellent biocompatibility and osteoconductivity. Immune response plays an important role in determining the internal outcome of β-TCP. β-TCP, as a foreign body, is recognized by the immune system and triggers different behavior patterns of immune cells, thus affecting the formation of new bone. It is helpful to understand the influence of immune environment and osteogenesis induced by β-TCP. In order to explore the optimal immune environment that provides balance between osteogenesis and osteoclastogenesis for osseointegration, this paper reviews the research of β-TCP in the field of bone immunology.

Key words: β-tricalcium phosphate, osteoimmunology, bone substitute, bone regeneration