Cleaning Efficacy of Andrographis Paniculata Nanoemulsion Irrigant on Root Canals

doi:10.13701/j.cnki.kqyxyj.2022.05.014

Abstract

Abstract: Objective: To evaluate the cleanliness of andrographis paniculata nanoemulsion for root canal irrigation. Methods: Fifty freshly extracted single-root canal premolars were collected and divided into five groups. During instrumentation,the nickel-titanium files,the crown-down preparation, and five irrigants were used. group A: andrographis paniculata nanoemulsion; group B: andrographis paniculata extract; group C: 1% NaClO; group D: 3% NaClO; and group E: 0.9% saline. All groups were finally irrigated with 17% EDTA and saline, respectively. Digital camera and scanning electron microscopy were used to compare the debris and smear layer scores in the apical, middle, and coronal thirds of the root canals. Results: In the apical thirds: group E showed higher debris and smear layer score than other four groups, group C had significantly higher smear layer score than group A and D (P<0.05). In the middle thirds: group C showed significantly more debris than group A and D (P<0.05). In the coronal thirds: group C had significantly higher smear layer score than group D (P<0.05). Conclusion: The cleanliness of the irrigation fluid was ranked as follows: 3% NaClO, andrographis paniculata nanoemulsion, andrographis paniculata extract, 1% NaClO, and Saline. Andrographis paniculata nanoemulsion appears to be one of the Chinese medicine to be identified as a possible intracanal irrigant.

Key words: andrographis paniculata nanoemulsion, root canal irrigation, debri, smear layer, scanning electron microscope

SUN Jia, HAN Wei, ZHANG Shuying, GUAN Tong, JIANG Mei, SHI Yan. Cleaning Efficacy of Andrographis Paniculata Nanoemulsion Irrigant on Root Canals[J]. Journal of Oral Science Research, 2022, 38(5): 459-464.

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