Journal of Oral Science Research ›› 2015, Vol. 31 ›› Issue (12): 1261-1263.

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Research Progress on Relationship between MicroRNA-7 and Tumor and Prospect of Its Application in Oral Malignant Tumors.

GUO Shuan-long, ZHANG Bin, LI Ying.   

  1. Sino-Russian Institute of Hard Tissue Development and Regeneration, the Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China
  • Received:2014-07-18 Online:2015-12-28 Published:2016-03-21

Abstract: MicroRNAs are small and noncoding RNAs with regulatory functions, about 21 to 25 nucleotides, which play an important role in many human diseases, including cancer. Recent studies indicate that abnormal expression of MicroRNA-7 exists in a wide variety of tumor cells, and the cell proliferation, invasion and metastasis ability changed after introducing manual MicroRNA-7 into tumor cells. In this paper, advances in the research of MicroRNA-7 in tumors are summarized, and reasonable prospect is presented on its application in oral and maxillofacial malignant tumor.

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