具核梭杆菌与口腔常见微生物粘附作用的研究进展

doi:10.13701/j.cnki.kqyxyj.2021.04.002

口腔医学研究 ›› 2021, Vol. 37 ›› Issue (4): 284-287.DOI: 10.13701/j.cnki.kqyxyj.2021.04.002

具核梭杆菌与口腔常见微生物粘附作用的研究进展

李懿洋, 周学东^*

口腔疾病研究国家重点实验室国家口腔疾病临床医学研究中心,四川大学华西口腔医院牙体牙髓病科四川成都 610041

收稿日期:2020-06-09 发布日期:2021-04-15
通讯作者: *周学东,E-mail:zhouxd@scu.edu.cn
作者简介:李懿洋(1993~ ),女,辽宁人,硕士在读,研究方向:口腔微生物。
基金资助:
国家自然科学基金(编号:81991500、81991501)

Overviews of Research on Coadherence between Fusobacterium Nucleatum and Common Oral Microorganisms

LI Yiyang, ZHOU Xuedong^*

State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases; Department of Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China

Received:2020-06-09 Published:2021-04-15

摘要/Abstract

摘要： 具核梭杆菌是口腔中含量最高的梭杆菌,可成为早期和晚期定植的微生物的连接桥梁,以共生菌的形式存在,也可成为致病菌参与口腔疾病的发生发展。具核梭杆菌与口腔微生物的相互作用可影响微生物与宿主细胞的相互作用,进而决定口腔的健康状态。粘附是最直接的相互作用方式,也是微生物进入生物膜和侵袭宿主细胞的第一步。本文就具核梭杆菌与口腔常见微生物的粘附作用及其相关机制的研究进行综述。

关键词: 具核梭杆菌, 粘附作用, 口腔微生物

Abstract: Fusobacterium nucleatum is the most common Fusobacterium species in the oral cavity. Fusobacterium nucleatum may exist as a type of commensal bacteria acting as a bridge between early and late colonizing bacteria. It can also act as pathogenic bacteria in the development of oral diseases. The interactions between Fusobacterium nucleatum and the other oral microbes may affect the interactions between oral microbes and host cells, which in turn determine the health of the host. Bacterial adhesion is the first step that bacteria integrate into the biofilms and then invade the host cells. This article reviews the coadherence and the possible interactions between Fusobacterium nucleatum and common oral microorganisms.

Key words: Fusobacterium nucleatum, coadherence, oral microorganisms

李懿洋, 周学东. 具核梭杆菌与口腔常见微生物粘附作用的研究进展[J]. 口腔医学研究, 2021, 37(4): 284-287.

LI Yiyang, ZHOU Xuedong. Overviews of Research on Coadherence between Fusobacterium Nucleatum and Common Oral Microorganisms[J]. Journal of Oral Science Research, 2021, 37(4): 284-287.

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具核梭杆菌与口腔常见微生物粘附作用的研究进展

Overviews of Research on Coadherence between Fusobacterium Nucleatum and Common Oral Microorganisms

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