口腔医学研究 ›› 2020, Vol. 36 ›› Issue (8): 713-715.DOI: 10.13701/j.cnki.kqyxyj.2020.08.002

• 综述 • 上一篇    下一篇

自体血小板浓缩物对周围神经再生的研究进展

王展麒1,2, 孙晓琳1,2*   

  1. 1. 吉林大学口腔医院种植科 吉林 长春 130021;
    2. 吉林省牙发育及颌骨重塑与再生重点实验室 吉林 长春 130021
  • 收稿日期:2019-07-26 出版日期:2020-08-28 发布日期:2020-08-18
  • 通讯作者: *孙晓琳,E-mail:sxl2673366@126.com
  • 作者简介:王展麒(1998~ ),男,吉林长春人,学士在读,研究方向:口腔种植学。
  • 基金资助:
    国家自然科学基金(编号:81570983);吉林大学博士研究生交叉学科科研资助计划项目(编号:10183201846)

Research Progress on Autologous Platelet Concentrates in Peripheral Nerve Regeneration

WANG Zhanqi1,2, SUN Xiaolin1,2*   

  1. 1. Department of Implant Center, Hospital of Stomatology, Jilin University, Changchun 130021, China;
    2. Provincial Key Laboratory of Dental Development, Jaw Remodeling and Regeneration, Jilin University, Changchun 130021, China
  • Received:2019-07-26 Online:2020-08-28 Published:2020-08-18

摘要: 种植手术过程中常可能造成周围神经损伤,随之出现支配区域的感觉及功能障碍,影响患者生活质量。自体血小板浓缩物是一类拥有独特生物学特性及特殊组织学结构的绝对内源性物质,众多学者提出将其作为一种新兴的生物材料应用于周围神经修复再生。本文就自体血小板浓缩物在周围神经再生中的作用机制及研究进展做一综述。

关键词: 血小板浓缩物, 雪旺细胞, 生长因子, 神经再生

Abstract: During implant surgeries, peripheral nerves may be injured. The sensory and functional disorder of the dominant area can affect the quality of patient's life. Autologous biological concentrate is a kind of absolute substance with unique biological characteristics and special histological structure. Many scholars have supported the hypothesis for its application in peripheral nerve regeneration after injury. In this review, we highlight the mechanism and progress of autologous platelet concentrates in peripheral nerve regeneration.

Key words: platelet concentrates, Schwann cells, growth factors, nerve regeneration