口腔医学研究

口腔医学研究 ›› 2021, Vol. 37 ›› Issue (11): 1004-1008.DOI: 10.13701/j.cnki.kqyxyj.2021.11.010

• 牙周病学研究 • 上一篇    下一篇

膳食习惯影响慢性牙周炎的多因素分析

鲁皓1, 李金凤2, 孙奇3, 戴江红4, 陈晓涛1*   

  1. 1.新疆维吾尔自治区人民医院口腔科 新疆 乌鲁木齐 830001;
    2.石河子大学医学院口腔医学系 新疆 石河子 832000;
    3.新疆医科大学第四附属医院 新疆 乌鲁木齐 830099;
    4.新疆医科大学公共卫生学院 新疆 乌鲁木齐 830011
  • 收稿日期:2021-03-24 出版日期:2021-11-28 发布日期:2021-11-22
  • 通讯作者: *陈晓涛,E-mail:1440945785@qq.com
  • 作者简介:鲁皓(1994~ ),医师,硕士在读,研究方向:牙周病病因学。
  • 基金资助:
    国家重点研发计划(编号:2017YFC0907200,2017YFC0907203)国家自然科学基金(编号:81660185)

Multivariate Analysis of Effect of Dietary Habits on Chronic Periodontitis

LU Hao1, LI Jinfeng2, SUN Qi3, DAI Jianghong4, CHEN Xiaotao1*   

  1. 1. Department of Stomatology, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, China;
    2. Department of Stomatology, School of Medicine, Shihezi University, Shihezi 832000, China;
    3. The Fourth Affiliated Hospital of Xinjiang Medical University, Urumqi 830099, China;
    4. School of Public Health, Xinjiang Medical University, Urumqi 830011, China
  • Received:2021-03-24 Online:2021-11-28 Published:2021-11-22

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摘要： 目的: 探索对慢性牙周炎结局产生影响的膳食类别及饮食方式。方法: 膳食数据来自中国西北区域自然人群队列研究(China Northwest Cohort, CNC)项目数据库,选取CP人群1000例。根据美国CDC慢性牙周炎诊断标准将研究人群分为4组:健康、轻、中和重度CP组。使用lasso回归从47个膳食变量筛选纳入单因素回归分析,再综合单因素回归和lasso回归二次筛选的结果纳入多因素回归模型。结果: 动物内脏每天摄入40~75 g发生CP的风险是摄入量小于40 g的1.70倍(95%CI:1.16~2.48,χ2=7.372,P=0.007)。与不食用葵花籽油相比,食用葵花籽油的OR值是1.58(95%CI:1.12~2.22,χ2=6.809,P=0.009)。以不吃油炸食品为对照,食用频率为1~3次/月的OR值是0.66(95%CI:0.43~1.01,χ2=3.605,P=0.058)。结论: 选择以动物内脏为单一肉类食物、葵花籽油过量摄入以及频率为1周1次以上的油炸类食物的摄入可能与CP的进展存在关联。

关键词: 膳食, 慢性牙周炎, lasso回归

Abstract: Objective: To explore the influencing factors of dietary types and dietary patterns on the outcome of chronic periodontitis (CP). Methods: The dietary data were collected from the project "China Northwest Cohort, CNC" database, and A total of 1000 CP people were selected. According to the American CDC's diagnostic criteria for chronic periodontitis, the study population was divided into four groups: healthy, mild, moderate, and severe CP groups. The lasso regression was used to screen 47 dietary variables. Only those variables demonstrating significance both in univariate regression and lasso regression were included in the multivariate regression model. Results: It was concluded that the risk of CP by consuming 40-75g of animal viscera per day was 1.70 times higher than that of intake less than 40 g (95%CI: 1.16-2.48, P<0.05). Compared with not eating sunflower oil, the OR of eating sunflower oil was 1.58 (95%CI: 1.12-2.22, P<0.05). Besides, compared with not eating fried food, the OR value of eating 1-3 times per month was 0.66 (95%CI: 0.43-1.01, P>0.05). Conclusion: The selection of animal viscera as the only meat food, excessive intake of sunflower oil, and fried foods with a frequency of more than once a week may associate with the progress of CP.

Key words: diet, chronic periodontitis, lasso regression