Abstract: Objective: To study the effect of thermal cycling on adhesive force of different cements to the implant-supported fixed bridge. Methods: 3D printing production of Cobalt-Chromium alloy implant-supported fixed bridges were divided into group A (composite resin cement) and group B (resin modified glass ionomer cement). Both group had 4 subgroups: thermal cycling 0 times (A1 and B1), thermal cycling 2500 times (A2 and B2), thermal cycling 5000 times (A3 and B3), and thermal cycling 10000 times (A4 and B4). Abutments were fixed to the implant analogs, and then the fixed bridges were bonded to the abutments. All the specimens were immersed in artificial saliva with 37℃ water bath for 24 hours after curing. The tensile test was used to measure the adhesive force of different cements to the implant-supported fixed bridge after thermal cycling. Results: The adhesive force of SAC were higher than Luting 2 before or after thermal cycling (P<0.05). The adhesive force of both cements were not significantly decreased after thermal cycling 2500 times (P>0.05). The adhesive force of both cements were significantly decreased after thermal cycling 5000 and 10000 times (P<0.05). Conclusion: Within the limits of this study, the adhesive performance of SAC is superior to Luting 2.