Journal of Oral Science Research ›› 2019, Vol. 35 ›› Issue (7): 619-624.DOI: 10.13701/j.cnki.kqyxyj.2019.07.001

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Preparation and Development of Three-dimensional (3D) Graphene Composite Scaffold in Bone Tissue Engineering

LIU Bin*, SONG Fuxiang   

  1. School and Hospital of Stomatology, Lanzhou University, Lanzhou 730000, China.
  • Received:2019-06-05 Online:2019-07-25 Published:2019-07-24

Abstract: With the rapid development of bone tissue engineering technology, different kinds of artificial scaffold have been successfully prepared for the repair of bone defects. The macro-porous scaffolds can effectively simulate the extracellular matrix (ECM) microenvironment, further promote the exchange of nutrients and metabolites, growth of tissue, and angiogenesis. It has a promising prospect in the field of bone tissue engineering. In recent years, the three-dimensional (3D) graphene-based composite scaffolds have become a research hotspot in the field of bone tissue engineering due to their large specific surface area, excellent biocompatibility, mechanical properties, and osteoconductivity. Therefore, this paper systematically reviewed and analyzed the preparation methods of 3D graphene scaffolds and the application of graphene-based composite scaffolds in the field of bone tissue engineering

Key words: three-dimensional, graphene, preparation, bone tissue engineering