Prognostic Factors of Primary Intraosseous Squamous Cell Carcinoma of the Jaw

doi:10.13701/j.cnki.kqyxyj.2019.12.008

Abstract

Abstract: Objective: To determine the prognostic factors of primary intraosseous squamous cell carcinoma(PIOSCC)of the jaw. Methods: Patients with PIOSCC of the jaw admitted to the Department of Oral and Maxillofacial Surgery,Affiliated Stomatological Hospital of Nanchang University (2012-2018) were selected as the study subjects. The clinical, radiological, and histopathological data of these patients were collected and followed up. Descriptive statistical analysis was used to determine the prognostic factors of the disease. Results: A total of 21 PIOSCC patients were included in this study. The mean age at diagnosis was 53.7 years (ranged from 41 to 77 years). Of the 21 patients, there were 13 males and 8 females, and 8 cases in maxilla and 13 cases in mandible. During the follow-up period, 2 cases were died of local recurrence and 5 cases were died of distant metastasis. The overall survival rate was 66.7%. Tumor size, cervical lymph node metastasis, and clinical stage of TNM were the negative prognostic factors. Conclusion: The prognosis of patients is poor if the tumor is more than 4 cm in size or with cervical lymph node metastasis.

Key words: primary intraosseous squamous cell carcinoma, prognosis

GUO Lingyan, CHEN Fen, WU Pingfan, LI Yu, LEI Zhengge, CHEN Linlin. Prognostic Factors of Primary Intraosseous Squamous Cell Carcinoma of the Jaw[J]. Journal of Oral Science Research, 2019, 35(12): 1132-1136.

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