Effects of Oxidative Stress on Oral Potentially Malignant Disorders

doi:10.13701/j.cnki.kqyxyj.2021.02.004

Abstract

Abstract: Oral potentially malignant disorders (OPMD) are clinical presentations that carry a risk of cancer development in the oral cavity, and its pathogenesis is still unclear. Studies have shown that oxidative stress (OS) is associated with the lipid peroxidation and DNA damage and the imbalance of antioxidant system in patients with oral lichen planus, oral leukoplakia, and oral submucosal fibrosis. The oxidative damage caused by reactive oxygen species (ROS) is closely related to the occurrence and development of them. Through the research of OS and these diseases, the pathogenesis of OS can be further clarified and new ideas for the prevention and antioxidant treatment of the disease can be provided.

Key words: oxidative stress, oral potentially malignant disorders, reactive oxygen species

SHA Tong, ZHANG Wei. Effects of Oxidative Stress on Oral Potentially Malignant Disorders[J]. Journal of Oral Science Research, 2021, 37(2): 109-112.

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