Journal of Oral Science Research ›› 2022, Vol. 38 ›› Issue (12): 1110-1114.DOI: 10.13701/j.cnki.kqyxyj.2022.12.002

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Research Progress on Role of Nerve in Repair of Damaged Dental Pulp

WANG Chunmeng, ZHANG Qi*   

  1. Department of Endodontics, School and Hospital of Stomatology, Tongji University, Shanghai Engineering Research Center of Tooth Restoration and Regeneration, Shanghai 200072, China
  • Received:2022-05-26 Online:2022-12-28 Published:2022-12-26

Abstract: The defense and self-repair function of pulp is the biological basis of damaged pulp repair and vital pulp therapy. As an important part of pulp tissue, nerve may play a role as the initiating factor after pulp injury. Pulp injury not only results in the changes of nerve distribution, structure, and signal transduction, but also affects other tissues and cells through related bioactive molecules. This article summarizes and discusses the role of nerve in pulp injury repair in recent years, with aid to provide reference and theoretical guidance for clinical treatment of vital pulp therapy.

Key words: pulp injury and repair, nerve, signal molecule, defense, repair