Journal of Oral Science Research ›› 2023, Vol. 39 ›› Issue (10): 917-922.DOI: 10.13701/j.cnki.kqyxyj.2023.10.013

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Preliminary Study on Deep Learning Picture Classification Model for Identification and Classification of Invasion Pattern of Oral Squamous Cell Carcinoma

WU Tianci1, YU Jiaxin1, HUANG Xiaofeng2, CHEN Sheng2, WANG Yuxin1, PU Yumei1*   

  1. 1. Department of Oral and Maxillofacial Surgery, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing 210008, China;
    2. Department of Oral Pathology, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing 210008, China
  • Received:2023-05-15 Online:2023-10-28 Published:2023-10-25

Abstract: Objective: To explore the feasibility and effect of the deep learning network model (ResNet-18) to determine the worst infiltration mode (worst pattern of invasion, WPOI) of oral squamous cell carcinoma (oral squamous cell carcinoma, OSCC). Methods: The 491 digital pathological sections collected by ResNet-18 model were trained to identify and distinguish non-tumor areas, WPOI 1-3 and WPOI 4-5, and the model was evaluated using the classification accuracy. Results: ResNet-18 neural network can effectively distinguish non-tumor areas of OSCC, WPOI 1-3 and WPOI 4-5, with an accuracy of 99.5%. Conclusion: The deep learning network model ResNet-18 can effectively distinguish the non-tumor areas of OSCC, WPOI 1-3, and WPOI 4-5, and assist physicians to improve the diagnosis speed.

Key words: oral squamous cell carcinoma, pathology, deep learning, ResNet, worst pattern of invasion