Review on the Role and Mechanism of Sox Gene in Oral Squamous Cell Carcinoma

doi:10.13701/j.cnki.kqyxyj.2022.04.004

Abstract

Abstract: Sox gene family is a kind of coding genes widely existed in human tissues. As an important transcription regulator, Sox protein not only participates in the whole process of animal growth and development, but also participates in the tumorigenesis and development of multiple system tumors including oral squamous cell carcinoma. In this paper, we reviewed the function of Sox gene in oral squamous cell cancer from the aspects of upstream and downstream interaction factors, related signal pathways, and clinical diagnosis and treatment potential, in order to provide new research direction and ideas for researchers.

Key words: Sox, oral squamous cell carcinoma, epithelial to mesenchymal transition

PENG Yanshuang, LIU Ying. Review on the Role and Mechanism of Sox Gene in Oral Squamous Cell Carcinoma[J]. Journal of Oral Science Research, 2022, 38(4): 312-315.

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