A Case Report of Eosinophilic Ulcer of Tongue

doi:10.13701/j.cnki.kqyxyj.2024.01.018

Abstract

Abstract: Eosinophilic ulcer of the tongue (EUT) is a relatively rare benign, reactive disease that typically exhibits self-limiting characteristics. Clinically, it often presents as a rapidly enlarging solitary ulcer, which is easily to be mistakenly diagnosed as a malignant tumor. This article presents a case of EUT that persisted for more than a month and explores its clinical and histopathological features, as well as the diagnostic and treatment approaches. The aim of this case is to provide valuable insights for the clinical management of this condition.

Key words: eosinophilic ulcer, traumatic ulcer, differential diagnosis

WEI Jingjing, TAN Yaqin, ZHOU Gang. A Case Report of Eosinophilic Ulcer of Tongue[J]. Journal of Oral Science Research, 2024, 40(1): 89-91.

References

[1] Shah SA, Kurago Z, Bindakhil M. Clinical considerations associated with traumatic ulcerative granuloma with stromal eosinophilia [J]. Int J Dermatol, 2022, 61(7):e272-e274.
[2] Aizic A, Raiser V, Solar I, et al. Traumatic ulcerative granuloma with stromal eosinophilia: CD30 analysis and clonality for T cell receptor gene re-arrangement [J]. Acta Histochem, 2019, 121(8):151450.
[3] Shapiro L, Juhlin EA. Eosinophilic ulcer of the tongue report of two cases and review of the literature [J]. Dermatologica, 1970, 140(4):242-250.
[4] Benitez B, Mülli J, Tzankov A, et al. Traumatic ulcerative granuloma with stromal eosinophilia-clinical case report, literature review, and differential diagnosis [J]. World J Surg Oncol, 2019, 17(1):184.
[5] SahanaPushpa T, Balamurugan R. Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE): a rare presentation and case report [J]. Can J Dent Hyg, 2022, 56(1):39-41.
[6] Vargo RJ, Qureshi A. A painful ulceration of the buccal mucosa [J]. J Am Dent Assoc, 2021, 152(10):866-871.
[7] Lakkam BD, Astekar M, Alam S, et al. Traumatic ulcerative granuloma with stromal eosinophilia: A puzzle [J]. J Oral Maxillofac Pathol, 2021, 25(Suppl 1):S42-S45.
[8] Bindakhil M, Alawi F, France K, et al. Primary syphilis of the oral cavity, a rare presentation of a re-emerging disease [J]. Cureus, 2021, 13(4):e14595.
[9] Misterska M, Dmochowski M, Szulczyska-Gabor J, et al. Eosinophilic ulcer of the oral mucosa: report of a child with CD30-negative cells in an infiltration on the lower lip [J]. Med Sci Monit, 2010, 16(8):CS95-CS99.
[10] Shokravi A, Özcan K, Ko YCK. Traumatic ulcerative granuloma with stromal eosinophilia of the soft palate: An unusual clinical presentation [J]. JAAD Case Rep, 2022, 29:169-172.
[11] el-Mofty SK, Swanson PE, Wick MR, et al. Eosinophilic ulcer of the oral mucosa. Report of 38 new cases with immunohistochemical observations [J]. Oral Surg Oral Med Oral Pathol, 1993, 75(6):716-722.
[12] Gonçales ES, Rubira-Bullen IF, Rubira CM, et al. Eosinophilic ulcer of the oral mucosa versus squamous cell carcinoma [J]. Quintessence Int, 2007, 38(8):677-680.
[13] Elovic AE, Gallagher GT, Kabani S, et al. Lack of TGF-alpha and TGF-beta 1 synthesis by human eosinophils in chronic oral ulcers [J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 1996, 81(6):672-681.
[14] Vijayakumar V, Reghunathan D, Edacheriyan B, et al. Role of toluidine blue staining in suspicious lesions of oral cavity and oropharynx [J]. Indian J Otolaryngol Head Neck Surg, 2019, 71(Suppl 1):142-146.
[15] Gupta M, Shrivastava K, Raghuvanshi V, et al. Application of in vivo stain of methylene blue as a diagnostic aid in the early detection and screening of oral cancerous and precancerous lesions [J]. J Oral Maxillofac Pathol, 2019, 23(2):304.
[16] Dhanrajani P, Cropley PW. Oral eosinophilic or traumatic ulcer: A case report and brief review [J]. Natl J Maxillofac Surg, 2015, 6(2):237-240.