Research Advances on Effect of Photobiomodulation Therapy on Root Resorption in Orthodontic Treatment

doi:10.13701/j.cnki.kqyxyj.2024.08.001

Abstract

Abstract: Root resorption is one of the most dangerous complications during orthodontic treatment. Mild root resorption can be repaired after removing force. However, there is no effective measure for severe root resorption. Photobiomodulation therapy, as a new physical therapy, has the advantages of small size, non-invasion, wide wavelength, limited scope of action, and biological safety. The range of its wavelength covers the range of mitochondrial absorption wavelength, and the biological activity of tissues or cells changes after being irradiated by red or near-infrared light, upregulating the anti-inflammatory and other related factors, promoting cellular ATP production, accelerating local blood microcirculation, promoting the repair of soft and hard tissues, and inhibiting or repairing resorbed tooth. The effect of photobiomodulation therapy depends on four elements, i.e. the parameter of the wavelength, energy density, power density, and irradiation frequency, obeying the "biphasic dose effect". Biological efficacy is parameter dependent, making it difficult to obtain optimal parameters. However, the unique advantages of photobiomodulation therapy make it have great application potential in the field of orthodontics.

Key words: photobiomodulation therapy, low level laser, root resorption, RANKL/RANK/OPG axis, parameter dependent

ZHANG Jiaxi, ZHANG Xizhong. Research Advances on Effect of Photobiomodulation Therapy on Root Resorption in Orthodontic Treatment[J]. Journal of Oral Science Research, 2024, 40(8): 665-669.

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