Abstract: Objective: To evaluate the cell toxicity and hemo-compatibility of the Zr based amorphous alloy with high strength and modulus of elasticity for dentistry. Methods: Zr based amorphous alloy was performed the hemolysis test by contacting with fresh human blood. MTT method was applied to study the cytotoxicity of this alloy. Results: The level of cell toxicity of Zr based amorphous alloy was 0, which meant no cell toxicity. The Zr based amorphous alloy had low hemolytic rate, long dynamic clotting time, similar anticoagulant capability to pure titanium and Ti6Al4V. The platelet adhesion test implied that Zr-Cu-Al-Ag alloy had seldom pseudopodium phenomenon. Conclusion: Zr-Cu-Al-Ag alloy has adequate cytocompatibilty and blood compatibility, which might meet the basic need of oral implantation.

Key words: Zr based amorphous alloy, Blood compatibility, Cytotoxicity