Abstract: Objective: To evaluate the effect of fiber laser systems on flexural strength and shear bond strength of zirconia ceramics. Methods: Fifty sintered zirconia ceramic blocks were prepared and divided into five groups (n=10). Group A: control group without treatment, Group B: air abrasion with Al2O3 particles, Group C to E: fiber laser with 2W, 4W, 6W power respectively. The flexural strength of all samples was measured and the microscopic morphology of each group was observed under SEM. After that, dual-cure composite resin cement Multilink N was bonded to the ceramic specimens and stored in distilled water at 37℃ for 24h. Mean values of shear bond strength (MPa) were calculated. Data were analyzed by one-way ANOVA and LSD tests (P<0.05). Results: The flexural strength did not show significant difference among the groups. The bond strength of group A and E were lower than that of group B, C, D (P<0.05). No significant differences were found among group B, C, D. Conclusion: This study shows that with proper laser power, fiber laser treatment can increase the bond strength of zirconia compared to the untreated group without affecting the flexural strength of the ceramics. Fiber laser may be an alternative method to pretreat zirconia ceramics in the clinic.