Relationship between Interleukin-34 and Periodontitis and Peri-implantitis

doi:10.13701/j.cnki.kqyxyj.2017.11.026

Abstract

Abstract: Periodontitis and peri-implantitis influence the periodontal tissues, and result in the supporting bone loss and even tooth and implant loss. Interleukin-34 is a tolerogenic cytokine sharing the same receptor--M-CSFR with M-CSF, and is a stimulator of osteoclasts differentiation that exerts synergistic effects with RANKL and might perform an important function in the occurrence and development of periodontitis and peri-implantitis. In this paper, the mechanism of bone resorption and immunoregulatory function of interleukin-34 is summarized, which is greatly significant for understanding the pathogenic mechanism and clinical treatment of periodontitis and peri-implantitis.

Key words: Interleukin-34, Periodontitis, Peri-implantitis

CLC Number:

R781.4

WU Li-li,Shi Qiu-tao,GU Zhi-yuan. Relationship between Interleukin-34 and Periodontitis and Peri-implantitis[J]. Journal of Oral Science Research, 2017, 33(11): 1234-1236.

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