Advances in Biomarkers Related to Orthodontic Tooth Movement in Gingival Crevicular Fluid

doi:10.13701/j.cnki.kqyxyj.2022.05.003

Abstract

Abstract: Gingival crevicular fluid is a kind of tissue permeation fluid in gingival sulcus and periodontal pocket. The application of orthodontic force to teeth will lead to remodeling of periodontal tissue and changes of biochemical mediators in gingival crevicular fluid. Analyzing the changes of specific biomarkers in gingival crevicular fluid during orthodontic tooth movement is helpful for doctors to understand the remodeling status of patients' periodontal tissue and monitor tooth movement, so as to develop personalized orthodontic treatment plan for patients, shorten the treatment period, and avoid adverse reactions. At present, the biological processes of biomarkers related to orthodontic tooth movement in gingival crevicular fluid can be divided into three categories: inflammation, bone resorption and formation, and tissue injury and repair. This article reviews the potential biomarkers related to orthodontic tooth movement in gingival crevicular fluid.

Key words: orthodontics, tooth movement, gingival crevicular fluid, biomarker, periodontium remodeling

GUAN Jiani, YAN Bin. Advances in Biomarkers Related to Orthodontic Tooth Movement in Gingival Crevicular Fluid[J]. Journal of Oral Science Research, 2022, 38(5): 400-403.

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