Short-term Curative Effect of Minocycline Gel and Hyaluronic Acid Gel as Adjunctive Treatment on Chronic Periodontitis

doi:10.13701/j.cnki.kqyxyj.2017.11.011

Abstract

Abstract: Objective: To compare the curative effects of two different gels as adjunctive treatment on chronic periodontitis. Methods: One hundred and five patients with chronic periodontitis in the Department of Stomatology of our hospital from June, 2012 to November, 2016 were randomly divided into three groups based on therapeutic prescription: group A (n=35, hyaluronic acid gel), group B (n=35, minocycline gel), and group C (n=35, SRP). After 3 months, the periodontal indexes, curative effect, and adverse drug reactions among three groups were compared. Results: Periodontal indexes in group A and B were significantly lower than that of group C (P<0.05). The PLI and percentage of spirochetes in sub-gingival plaque of group B at the 4th week after treatment were obviously lower than those of other two groups (P<0.05). The curative rates of group A and B were obviously higher than that of C group (P<0.05). The incidence of adverse drug reactions in group A was obviously lower than that of group B (P<0.05). Conclusion: These two different gels had similar curative effect as adjunctive treatment on chronic periodontitis.

Key words: Chronic periodontitis, Minocycline gel, Hyaluronic acid gel, Curative effect

CLC Number:

R781.4

CHEN Fan, Zhang Yong. Short-term Curative Effect of Minocycline Gel and Hyaluronic Acid Gel as Adjunctive Treatment on Chronic Periodontitis[J]. Journal of Oral Science Research, 2017, 33(11): 1177-1180.

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