Application of Triple Antibiotic Paste in Pulp Regeneration of Young Permanent Teeth

doi:10.13701/j.cnki.kqyxyj.2019.07.003

Abstract

Abstract: Pulp regeneration has been admitted as an effective treatment of pulpitis and periapical inflammation of young permanent teeth in recent years. The root canal system and periapical region infection control, the key of successful pulp regeneration, becomes a public concern. Triple antibiotic paste (TAP) contains metronidazole, ciprofloxacin, and minocycline. With the appropriate working concentration and time, it could achieve an ideal bacterial inhibitory effect, sterilize the root canal system, minimize cell toxicity, facilitate pulp tissue conversation and regeneration, and promote the root and related tooth hard tissues development. However, there are also some disadvantages of TAP such as tooth discoloration, drug resistance, and etc. This review would summarize the application and characteristics of TAP in the pulp regeneration of young permanent teeth

Key words: triple antibiotic paste, pulp regeneration, infection control, root canal system disinfection

XU Jingchen, HUANG Ruijie. Application of Triple Antibiotic Paste in Pulp Regeneration of Young Permanent Teeth[J]. Journal of Oral Science Research, 2019, 35(7): 629-631.

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