Journal of Oral Science Research ›› 2019, Vol. 35 ›› Issue (10): 928-930.DOI: 10.13701/j.cnki.kqyxyj.2019.10.005

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Progress on Mechanism for the Effect of Estrogen on Periodontal Tissues

LI Zhibang1, LI Kun2*   

  1. 1. Medical Team of 66081 Troops, Zhangjiakou 075400, China;
    2. Department of Periodontology, Jinan Stomatological Hospital, Jinan 250002, China.
  • Received:2019-02-13 Online:2019-10-28 Published:2019-10-22

Abstract: The discovery of estrogen receptors in periodontal tissue provides direct evidence that estrogen is associated with periodontal health. Current studies also show that estrogen has effect on both innate immunity and adaptive immunity. Estrogen is protective on alveolar bone, and estrogen deficiency may lead to decrease of alveolar bone density and teeth loss. Estrogen can also influence the function of periodontal ligament stem cells. Exploring the mechanism of estrogen on periodontal tissues is helpful for further clarifying the pathogenesis of periodontal diseases, and it is beneficial to the prevention and treatment of estrogen-related periodontal diseases as well.

Key words: estrogen, periodontal tissue, immune system, alveolar bone