[1] Page RC, Kornman KS. The pathogenesis of human periodontitis:An introduction [J]. Periodontol 2000, 1997, 14(1):9-11.
[2] Liu J, Wang X, Zheng M, et al. Lipopolysaccharide from Porphyromonas gingivalis promotes autophagy of human gingival fibroblasts through the PI3K/Akt/mTOR signaling pathway [J]. Life Sci, 2018,211:133–139.
[3] 任静宜,刘歆婵,丁烨,等.细胞自噬和炎症反应的相互调控与牙周炎[J].国际口腔医学杂志,2016,43(4):462-466.
[4] Francesca G, Sadia A, Forbes-Hernandez TY, et al. Autophagy in human health and disease: novel therapeutic opportunities [J]. Antioxid Redox Signal, 2019, 30(4):577-634.
[5] Couve E, Osorio R, Schmachtenberg O.The amazing odontoblast: activity, autophagy, and aging [J]. J Dent Res, 2013, 92(9):765-772.
[6] Levine B, Kroemer G. Autophagy in the pathogenesis of disease [J]. Cell, 2008, 132(1):27-42.
[7] Hamacher-Brady A. Autophagy regulation and integration with cell signaling [J]. Antioxid Redox Signal, 2012, 17(5):756-765.
[8] Kim KH, Lee MS. Autophagy-a key player in cellular and body metabolism [J]. Nat Rev Endocrinol, 2014, 10(6):322-337.
[9] Galluzzi L, Baehrecke EH, Ballabio A, et al. Molecular definitions of autophagy and related processes [J]. EMBO J, 2017, 36(13):1811-1836.
[10] Frake RA, Ricketts T, Menzies FM, et al. Autophagy and neurodegeneration [J]. J Clin Invest, 2015, 125(1): 65-74.
[11] Panda PK, Mukhopadhyay S, Das DN, et al. Mechanism of autophagic regulation in carcinogenesis and cancer therapeutics [J]. Semin Cell Dev Biol, 2015, 39: 43-55.
[12] Bullon P, Cordero MD, Quiles JL, et al.Autophagy in periodontitis patients and gingival fibroblasts: unraveling the link between chronic diseases and inflammation [J]. BMC Med, 2012, 10(1):122.
[13] An Y, Liu W, Xue P, et al. Increased autophagy is required to protect periodontal ligament stem cells from apoptosis in inflammatory microenvironment [J]. J Clin Periodontol, 2016, 43(7):618-625.
[14] Wei W, An Y, An Y, et al. Activation of autophagy in periodontal ligament mesenchymal stem cells promotes angiogenesis in periodontitis [J]. J Periodontol, 2018, 89(6):718-727.
[15] Amano A, Chen C, Honma K, et al. Genetic characteristics and pathogenic mechanisms of periodontal pathogens [J]. Adv Dent Res, 2014, 26(1):15-22.
[16] Galluzzi L, José Manuel, Levine B, et al. Pharmacological modulation of autophagy: Therapeutic potential and persisting obstacles [J]. Nat Rev Drug Discov, 2017, 16(7):487-511.
[17] Fredman G, Oh SF, Ayilavarapu S, et al. Impaired phagocytosis in localized aggressive periodontitis: rescue by resolvin E1 [J]. PLoS One, 2011, 6(9): e24422.
[18] Wang CW, Colas RA, Dalli JP, et al. Maresin1 biosynthesis and pro-resolving anti-infective functions with human localized aggressive periodontitis leukocytes [J]. Infect Immun, 2015, 84(3):658-665.
[19] Luo LJ, Liu F, Lin ZK, et al.Genistein regulates the IL-1 beta induced activation of MAPKs in human periodontal ligament cells through G protein-coupled receptor 30 [J]. Arch Biochem Biophys, 2012, 522(1):9-16.
[20] Choi EY, Bae SH, Ha MH, et al. Genistein suppresses Prevotella intermedia lipopolysaccharide induced inflammatory response in macrophages and attenuates alveolar bone loss in ligature induced periodontitis [J]. Arch Oral Biol, 2016, 62:70-79.
[21] Li S, Hao L, Wang L, et al. Targeting Atp6v1c1 prevents inflammation and bone erosion caused by periodontitis and reveals its critical function in osteoimmunology [J]. PLoS One, 2015, 10(8): e0134903.
[22] Nelson KM, Dahlin JL, Bisson J, et al. The essential medicinal chemistry of curcumin [J]. J Med Chem, 2017, 60(5):1620-1637.
[23] Kocaadam B, Şnlier N. Curcumin, an active component of turmeric (Curcuma longa), and its effects on health [J]. Crit Rev Food Sci Nutr, 2017, 7(13):2889-2895.
[24] Sekiya M, Shimoyama Y, Ishikawa T, et al. Porphyromonas gingivalis, is highly sensitive to inhibitors of a proton-pumping ATPase [J]. Biochem Biophys Res Commun, 2018, 498(4):837-841.
[25] Brzezinski A. Melatonin in humans [J]. N Engl J Med,1997, 336:186-195.
[26] Rodriguez C, Mayo JC, Sainz RM, et al. Regulation of antioxidant enzymes: a significant role for melatonin [J]. J Pineal Res, 2004, 36(1):1-9.
[27] Nopparat C, Sinjanakhom P, Govitrapong P. Melatonin reverses H2O2 -induced senescence in SH-SY5Y cells by enhancing autophagy via sirtuin 1 deacetylation of the RelA/p65 subunit of NF-κB [J]. J Pineal Res, 2017,63(1).
[28] Virto L, Haugen HJ, Fernández-Mateos P, et al. Melatonin expression in periodontitis and obesity: An experimental in-vivo investigation [J]. J Periodontal Res, 2018, 3(5):825-831.
[29] Kara A, Akman S, Ozkanlar S, et al. Immune modulatory and antioxidant effects of melatonin in experimental periodontitis in rats [J]. Free Radic Biol Med, 2013, 55:21-26.
[30] Saxton RA, Sabatini DM. mTOR signaling in growth, metabolism, and disease [J]. Cell, 2017, 168(6):960-976.
[31] Xia Y, Sun M, Xie Y, et al. mTOR inhibition rejuvenates the aging gingival fibroblasts through alleviating oxidative stress [J]. Oxid Med Cell Longev, 2017, 2017:6292630.
[32] An JY, Quarles EK, Mekvanich S, et al. Rapamycin treatment attenuates age-associated periodontitis in mice [J] Geroscience, 2017, 39(4):457-463.
[33] 顾杏花,马铭阳,于丰,等.慢性牙周炎与阿尔茨海默氏病关系的研究进展[J].牙体牙髓牙周病学杂志,2018,28(6):364-368. |