Clinical Effect of CGF Application on Palatal Wound Healing after Free Gingival Graft Harvesting

doi:10.13701/j.cnki.kqyxyj.2021.12.016

Abstract

Abstract: Objective: To compare the healing effect between concentrated growth factor (CGF) membranes and conventional treatment for palatal wounds, resulting from free gingival graft (FGG) harvesting. Methods: Thirty patients requiring FGG were included in this study. After FGG harvesting, CGF group (n=16) received CGF membranes and iodoform sponges at the palatal wound while control group (n=14) only receiving iodoform sponges. Wound healing area of the palatal wound, mucosal condition, and postoperative pain were assessed 3, 7, 14, and 30 days after operation. Results: CGF group healed better on the palatal wound (P＜0.05) than that of control group except for 3 days of follow-up. As for postsurgical mucosal state, CGF group had more favorable outcomes immediately after operation and 3 and 7 days postoperation (P＜0.05). At 30 days postoperation, both groups showed total recovery. Further, control group experienced higher pain level and discomfort P＜0.05) until the 14th day. Conclusion: CGF membranes significantly promote the healing process and soothe the postsurgical pain for palatal wound healing.

Key words: concentrated growth factor, wound healing, pain, free gingival graft

LIANG Yuan, LUO Yi, SHEN Jingtao, WANG Si, ZHOU Qiao. Clinical Effect of CGF Application on Palatal Wound Healing after Free Gingival Graft Harvesting[J]. Journal of Oral Science Research, 2021, 37(12): 1135-1138.

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