Abstract: Orofacial granulomatosis is an uncommon chronic idiopathic granulomatous disease whose manifestations are characterized by persistent swelling of the orofacial soft tissues. The etiology and pathogenesis of orofacial granulomatosis is unclear. Meanwhile, a consensual and standardized diagnosis and treatment of this disease is lacking. Here we report a case presented with labial and chin swelling which was confirmed to be orofacial granulomatosis, aiming to provide reference for clinical management of the disease.

Key words: orofacial granulomatosis, cheilitis, management