口腔医学研究 ›› 2022, Vol. 38 ›› Issue (10): 907-912.DOI: 10.13701/j.cnki.kqyxyj.2022.10.001

• 特约述评 •    下一篇

对正畸诱导性牙根吸收生物层面的认识

贺红*, 杜明远   

  1. 武汉大学口腔医学院正畸一科,武汉大学口腔医学院口腔基础医学省部共建国家重点实验室培育基地,口腔生物医学教育部重点实验室 湖北 武汉 430079
  • 收稿日期:2022-07-15 出版日期:2022-10-28 发布日期:2022-10-20
  • 通讯作者: *贺红,E-mail:drhehong@whu.edu.cn
  • 作者简介:贺红,博士,教授,一级主任医师,博士生导师,武汉大学口腔医学院正畸教研室主任、正畸一科主任。现任中华口腔医学会正畸专委会副主任委员;中国医师协会睡眠专委会副主任委员;中华口腔医学会唇腭裂专委会常委;国际牙医师学院院士(FICD);英国皇家爱丁堡牙外科学院正畸院员(MorthRCS)及考试委员会委员;香港大学牙学院名誉教授。
  • 基金资助:
    国家自然科学基金(编号: 81970970、82001089)

Biological Insights into Orthodontically Induced Root Resorption

HE Hong*, DU Mingyuan   

  1. Department of Orthodontics, School and Hospital of Stomatology, The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China
  • Received:2022-07-15 Online:2022-10-28 Published:2022-10-20

摘要: 正畸诱导性牙根吸收是正畸矫治力引发的以牙骨质等牙体组织破坏为主要特征的常见并发症,其主要由正畸矫治力诱导的局部无菌炎症而引起,进展过程受到了多种细胞及相关分子的复杂调控。由于正畸诱导性牙根吸收发病率高,潜在影响患者牙周组织健康,因此应受到正畸医生高度重视。本文着重于从生物层面对正畸诱导性牙根吸收进展特点、主要参与的细胞和相关调控分子及牙骨质的修复进行讨论。

关键词: 正畸诱导性牙根吸收, 牙骨质, 无菌性炎症

Abstract: Orthodontically induced root resorption is a common complication caused by orthodontic force, which is mainly characterized by the destruction of cementum and other dental tissues. It is mainly caused by local aseptic inflammation induced by orthodontic force and regulated by multiple cells and related molecules. Orthodontically induced root resorption is highly concerned by orthodontists due to its high incidence and potential impact on the health of periodontal tissues. In this article, biological characteristics of the progress of orthodontically induced root resorption, the main involved cells, related regulatory molecules, and cementum repair are described.

Key words: orthodontically induced root resorption, cementum, aseptic inflammation