口腔医学研究

口腔医学研究 ›› 2022, Vol. 38 ›› Issue (11): 1047-1051.DOI: 10.13701/j.cnki.kqyxyj.2022.11.010

• 口腔种植学研究 • 上一篇    下一篇

器官移植患者牙列缺损种植义齿修复效果的研究

罗善峰*, 张侃, 钱志江, 倪振芳   

  1. 浙江省绍兴市口腔医院种植科 浙江 绍兴 312000
  • 收稿日期:2022-08-25 出版日期:2022-11-25 发布日期:2022-11-22
  • 通讯作者: *罗善峰,E-mail:93405661@qq.com
  • 作者简介:罗善峰(1982~ ),男,浙江绍兴人,硕士,副主任医师,主要从事口腔种植学研究工作。

Clinical Effect and Safety of Dental Implant Treatment on Kidney Transplanted Patient

LUO Shanfeng*, ZHANG Kan, QIAN Zhijiang, NI Zhenfang   

  1. Department of Oral Implantology Stomatological Hospital of Shaoxing, Shaoxing 312000, China
  • Received:2022-08-25 Online:2022-11-25 Published:2022-11-22

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摘要： 目的: 探讨器官移植患者种植义齿修复的安全性及效果。方法: 选择2010年1月~2020年12月在本院就诊的器官移植后2年,且各项检查指标均在正常范围内的牙列缺损拟种植义齿修复患者6例,共计植入15颗种植体。观察术后伤口愈合、肝肾功能、血尿常规、免疫抑制剂浓度、种植体-骨整合及义齿行使咀嚼功能后种植体周骨吸收、牙龈健康状况等。结果: 在为期3~10年的观察中,所有种植体均达到骨整合,2颗种植体术后伤口愈合欠佳,术后3年内肝肾功能、血尿常规未见明显变化,免疫抑制剂浓度有一定程度波动。2例患者义齿修复后第5年(肾移植后第9~12年)出现蛋白尿+及血尿++。义齿修复后第1、5、8年种植体周骨吸收分别为(0.81±0.19) mm、(1.02±0.29) mm、(1.54±0.37) mm,种植体周袋深度分别为(1.63±0.77) mm、(1.92±0.59) mm、(2.32±0.46) mm,差异没有统计学意义。义齿修复后第5年有1颗种植体失去骨整合,7颗修复体因邻牙松动出现食物嵌塞。结论: 在严格控制适应症并做好术前准备和术后处理的情况下,器官移植患者可以行种植义齿修复,且可取得比较理想的远期效果。

关键词: 肾移植, 牙种植, 免疫抑制剂, 安全性, 效果

Abstract: Objective: To explore the effect and safety of dental implant treatment on the kidney transplantation patients. Methods: Six patients who had kidney transplantation for 2 years were selected. Fifteen dental implants were inserted. The wound heal, hepatorenal function, abbreviation for blood and urine routine, concentration of FK506, implant osseointegration, and bone resorption were recorded at every review time. Results: All implants obtained osseointegration in the 3-10 years' follow-up. There were no changes in hepatorenal function, abbreviation for blood, and urine routine in the 3 years' follow-up. Urine protein positive and hematuresis were found in 2 patients after 5 years. One implant lost osseointegration after 8 years. The bone resorption around implants after 1, 5, and 8 years were (0.81±0.19) mm, (1.02±0.29) mm, and (1.54±0.37) mm. The PD was (1.63±0.77) mm, (1.92±0.59) mm, and (2.32±0.46) mm. There was no significant difference between each follow-up. Conclusion: An ideal function of dental implant restoration may be acquired for patients with kidney transplantation, provided that preoperative and postoperative infection was prevented and the indication was strictly controlled.

Key words: kidney transplantation, dental implant, immunosuppressant, safety, effect