[1] Hershko A, Ciechanover A. The ubiquitin system [J]. Annu Rev Biochem,1998,67∶425-479 [2] Zeng T,Wang Q,Fu J,et a1.hnpeded nedd4 1 mediated ras degradation underlies ras driven tumorigenesis [J]. Cell Rep, 2014, 7∶871-882 [3] Mei Z, Zhang D, Hu B, Wang J, Shen X, Xiao W. FBXO32 Targets c-Myc for Proteasomal Degradation and Inhibits c-Myc Activity [J]. J Biol Chem,2015,290(26)∶16202-14 [4] YE Y, RAPE M. Building ubiquitin chains: E2 enzymes at work [J]. Nature reviews Molecular cell biology, 2009, 10(11): 755-64.; Malynn BA, Ma A. Ubiquitin makes its mark on immune regulation [J]. Immunity, 2010, 33(6)∶843-52 [5] Christensen DE, Brzovic PS, Klevit RE. E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages [J]. Nature structural & molecular biology, 2007, 14(10)∶941-8 [6] CHRISTENSEN D E, KLEVIT R E. Dynamic interactions of proteins in complex networks: identifying the complete set of interacting E2s for functional investigation of E3-dependent protein ubiquitination. The FEBS journal, 2009, 276(19)∶5381-9 [7] Komander D, Rape M. The ubiquitin code [J]. Annu Rev Biochem, 2012, 81∶203-229 [8] Huang L, Kinnucan E, Wang G, et al. Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade [J]. Science, 1999, 286∶1321-1326 [9] Deshaies RJ, Joazeiro CA. RING domain E3 ubiquitin ligases [J]. Annual review of biochemistry, 2009, 78∶399-434 [10] Rotin D, Kumar S. Physiological functions of the HECT family of ubiquitin ligases [J]. Nature reviews Molecular cell biology, 2009, 10(6)∶398-409 [11] Ye Y, Rape M. Building ubiquitin chains: E2 enzymes at work [J]. Nat Rev Mol Cell Biol, 2009, 10∶755-764 [12] Kim HC, Huibregtse JM. Polyubiquitination by HECT E3s and the determinants of chain type specificity [J]. Mol Cell Biol, 2009, 29∶3307-3318 [13] E3 ubiquitin ligase RNF126 promotes cancer cell proliferation by targeting the tumor suppressor p21 for ubiquitin-mediated degradation [14] 孙国文,张笑佛,李田,等.Hedgehog信号通路效应蛋白在舌癌组织中的表达及意义[J].口腔医学研究,2015,31(4)∶393-396 |