Abstract: Objective: To observe the clinical efficacy of iRoot BP plus pulp capping treatment for deep caries of permanent teeth after 3 years, and to explore the feasibility and influencing factors of this treatment method. Methods: One hundred and twelve mature permanent teeth diagnosed with deep caries or reversible pulpitis were selected from our department from January 2019 to September 2020. The caries were selectively removed under a dental surgical microscope and pulp capping treatment was completed. The follow-up period was more than 3 years, and the treatment effect was evaluated through imaging examinations and clinical indicators. Kaplan Meier survival analysis was used to calculate the survival rate of live pulp, and χ² test was used to examine the impact of various variables on clinical efficacy. Results: The Kaplan Meier survival curve showed that the 3-year survival rate of 112 mature permanent teeth after pulp capping was 91.1%, 82 affected teeth underwent indirect pulp capping, and 30 affected teeth underwent direct pulp capping after pulp exposure during caries removal. The 3-year survival rates were 92.7% and 86.7%, respectively. The efficacy of pulp capping was not correlated with gender, age, preoperative diagnosis, tooth type (anterior teeth, premolars, molars), cavity shape (Class Ⅰ, Ⅱ, Ⅲ), tooth position, and pulp capping method (P>0.05). Conclusion: iRoot BP plus as a pulp capping agent has a good therapeutic effect on mature permanent teeth diagnosed with deep caries or reversible pulpitis, and the study variables have no significant impact on prognosis.

Key words: pulp capping treatment, mature permanent teeth, selective caries removal, iRoot BP plus, dental surgery microscope