Abstract: Maintaining and regenerating alveolar bone height and width after tooth extraction directly affect the effect of implant restoration. Micro computed tomography (Micro-CT) technology, with its high resolution, three-dimensional imaging, and quantitative analysis, is a key tool for evaluating site preservation. However, due to the variety in animal models, programs, image acquisition methods, and analysis methods, it is hard to compare the effectiveness of different surgeries or bone regeneration materials. This leads to challenges in making optimal decisions from current research findings. This article reviews the placement and fixation of samples, selection of device parameters, region of interest delineation, significance and selection quantitative indicators in post-extraction site of preservation animal models, based on the composition and working principles of the Micro-CT imaging system and the selection of animal models. It also summarizes the direction of future technological developments and challenges, aiming to promote the standardization of Micro-CT technology in alveolar bone preservation research and improve the accuracy, repeatability, and comparability of data analysis.

Key words: Micro-CT, site preservation, animal model, quantitative analysis, alveolar bone defect