Effect and Progress of Autophagy Induced by Nanoparticles on Inhibition of Tumor Growth and Treatment

doi:10.13701/j.cnki.kqyxyj.2017.11.025

Abstract

Abstract: Cell autophagy is an important physiological response of cell self-regulation. It is closely related to nanoparticles. In recent years, nanoparticle and autophagy have become a hotspot in biomedical research. The results show that the effective induction of autophagy by nanoparticles in the specific cells can accelerate the death of diseased cells, which has important significance for the treatment of tumors and nervous system diseases. In this paper, the progress of autophagy and apoptosis and the mechanism of autophagy and apoptosis were introduced. The autophagy induced by different nanoparticles was discussed. The application of nanomaterials in autophagy was also discussed. It is our duty to focus on the study of mechanism of nanoparticle and cell autophagy and the controllability of nanoparticles so as to better apply to life science and help to cure diseases.

Key words: Autophagy, Apoptosis, Nanoparticles, Toxicity

CLC Number:

R780.2

WANG Yi-bo, SUN Bing, WANG Dan-dan, TANG Qi, SUN Hong-chen. Effect and Progress of Autophagy Induced by Nanoparticles on Inhibition of Tumor Growth and Treatment[J]. Journal of Oral Science Research, 2017, 33(11): 1230-1233.

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