Role and Mechanisms of Oral Bacterial Extracellular Vesicles in Microbiota-host Interactions

doi:10.13701/j.cnki.kqyxyj.2026.09.001

Abstract

Abstract: Bacterial extracellular vesicles (BEVs) are pivotal in oral disease pathogenesis. Research demonstrates their critical role in microbiota-host interactions, directly driving the development of periodontitis, dental caries, and oral cancer. These insights refine pathogenic models and inform novel targeted interventions. This review systematically summarizes BEV-mediated interaction mechanisms, analyzes their molecular roles in specific oral diseases, and explores translational applications in prevention and targeted therapy.

Key words: oral microbiota, extracellular vesicles, microbiota-host interactions, oral diseases

GONG Haochen, ZHOU Jieyu. Role and Mechanisms of Oral Bacterial Extracellular Vesicles in Microbiota-host Interactions[J]. Journal of Oral Science Research, 2026, 42(9): 733-739.

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