Application of Stem Cells from Human Exfoliated Deciduous Teeth in the Treatment of Oral and Maxillofacial Diseases

doi:10.13701/j.cnki.kqyxyj.2022.07.004

Abstract

Abstract: Stem cells from human exfoliated deciduous teeth (SHEDs), a kind of odontogenic mesenchymal stem cells characterized by easy acquisition and high expansion efficiency, can differentiate into a variety of cells, form different tissues, and secrete a range of functional cellular activity factors. They can also regulate immunity, resist apoptosis, and facilitate tissue repair and regeneration. With diversified and intense research, the potential of SHEDs in the treatment of refractory diseases has been established, and SHEDs are now considered as one of the promising seed cells in tissue engineering and stem cell therapy. This study aims to elaborate the biological characteristics and advantages of SHEDs, and discuss their use in oral-maxillofacial diseases and research progress.

Key words: stem cells from human exfoliated deciduous teeth, oral diseases, tissue regeneration

PAN Lu, LIANG Yan. Application of Stem Cells from Human Exfoliated Deciduous Teeth in the Treatment of Oral and Maxillofacial Diseases[J]. Journal of Oral Science Research, 2022, 38(7): 605-608.

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