Correlation between Carbonic Anhydrase Ⅵ Level and Dental Caries among Children Aged 4-5 Years.

doi:10.13701/j.cnki.kqyxyj.2018.04.007

Abstract

Abstract: Objective: To investigate the relationship between dental caries and CA-Ⅵ levels in saliva and dental plaque fluid in children aged 4-5 years. Methods: Thirty-three children were randomly selected for each group: caries-free group, low caries group, and high caries group. The levels of CA-Ⅵ in dental plaque and saliva were examined by ELISA. The pH values of dental plaque fluid were detected by H+-ISFET. The results were statistically analyzed. Results: The CA-Ⅵ levels in saliva were statistically different among three groups: caries-free group>low caries group>high caries group (P<0.05). The CA-Ⅵ levels in dental plaque fluid were significantly different among three groups: caries-free group>low caries group>high caries group (P<0.05). Pearson's correlation analysis showed CA-Ⅵ levels in saliva and dental plaque fluid were positively related to pH values of dental plaque fluid (P<0.001). Conclusion: With the increase of caries severity, the levels of CA-Ⅵ in saliva and dental plaque fluid decreased. CA-Ⅵ might increase the pH values of plaque on the dental surface, and play an important role in tooth protection and caries resistance.

Key words: Carbonic Anhydrase Ⅵ, Dental caries, Dental plaque, Saliva

HOU Wen, SU Da, QUE Guo-ying. Correlation between Carbonic Anhydrase Ⅵ Level and Dental Caries among Children Aged 4-5 Years.[J]. Journal of Oral Science Research, 2018, 34(4): 363-366.

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