Research Progress of Chondrogenic Progenitor Cells

doi:10.13701/j.cnki.kqyxyj.2018.11.002

Abstract

Abstract: Cartilage tissue has long been considered to be lack of self-healing capacity, and chondrocyte is considered to be the only cells in cartilage tissue. It is often easy to leave long-term pain and dysfunction after cartilage injury. However, with existing treatments, there are still difficulties to achieve a satisfactory outcome, which seriously affects patients' life quality. In recent years, with the development of biotechnology, tissue engineering, molecular biology technology, and stem cell therapy, the basic research in cartilage tissue made the breakthrough that provides new plans for treatments of cartilage injury. This thesis reviews the progress of research in cartilage stem cells. Currently, there is controversy about the nomenclature of stem cells derived from cartilage tissue. Therefore, chondrogenic progenitor cells (CPCs) is used in this thesis to describe cartilage stem cells.

Key words: Cartilage, Stem cell, Cartilage injury

TAN Pei-jie, ZHU Song-song. Research Progress of Chondrogenic Progenitor Cells[J]. Journal of Oral Science Research, 2018, 34(11): 1154-1157.

References

[1] Barbero A, Ploegert S, Heberer M, et al. Plasticity of clonal populations of dedifferentiated adult human articular chondrocytes [J]. Arthritis and rheumatism, 2003, 48(5)∶1315-1325
[2] Alsalameh S, Amin R, Gemba T, et al.Identification of mesenchymal progenitor cells in normal and osteoarthritic human articular cartilage [J]. Arthritis Rheum, 2004, 50(5)∶1522-1532
[3] Fickert S, Fiedler J, Brenner RE.Identification of subpopulations with characteristics of mesenchymal progenitor cells from human osteoarthritic cartilage using triple staining for cell surface markers [J]. Arthritis Res Ther, 2004, 6(5)∶R422-R432
[4] Hattori S, Oxford C, Reddi AH.Identification of superficial zone articular chondrocyte stem/progenitor cells [J]. Biochem Biophys Res Commun, 2007, 358(1)∶99-103
[5] Koelling S, Kruegel J, Irmer M, et al.Migratory chondrogenic progenitor cells from repair tissue during the later stages of human osteoarthritis [J]. Cell Stem Cell,2009,4(4)∶324-335
[6] Seol D, Mccabe DJ, Choe H, et al.Chondrogenic progenitor cells respond to cartilage injury [J]. Arthritis Rheum, 2012, 64(11)∶3626-3637
[7] Williams R, Khan IM, Richardson K, et al.Identification and clonal characterisation of a progenitor cell sub-population in normal human articular cartilage [J]. PLoS One, 2010, 5(10)∶e13246
[8] Hung SC, Kuo PY, Chang CF, et al. Alpha-smooth muscle actin expression and structure integrity in chondrogenesis of human mesenchymal stem cells [J]. Cell Tissue Res, 2006, 324(3)∶457-466
[9] Karlsson C, Stenhamre H, Sandstedt J, et al. Neither notch1 expression nor cellular size correlate with mesenchymal stem cell properties of adult articular chondrocytes [J]. Cells Tissues Organs, 2008, 187(4)∶275-285
[10] Dominici M, Le Blanc K, Mueller I, et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement [J]. Cytotherapy, 2006, 8(4)∶315-317
[11] Diaz-Romero J, Gaillard JP, Grogan SP, et al. Immunophenotypic analysis of human articular chondrocytes: Changes in surface markers associated with cell expansion in monolayer culture [J]. J Cell Physiol, 2005, 202(3)∶731-742
[12] Grogan SP, Barbero A, Diaz-Romero J, et al. Identification of markers to characterize and sort human articular chondrocytes with enhanced in vitro chondrogenic capacity [J]. Arthritis Rheum, 2007, 56(2)∶586-595
[13] Wu L, Bluguermann C, Kyupelyan L, et al. Human developmental chondrogenesis as a basis for engineering chondrocytes from pluripotent stem cells [J]. Stem Cell Reports, 2013, 1(6)∶575-589
[14] Grogan SP, Duffy SF, Pauli C, et al. Zone-specific gene expression patterns in articular cartilage [J]. Arthritis Rheum, 2013, 65(2)∶418-428
[15] Dowthwaite GP, Bishop JC, Redman SN, et al. The surface of articular cartilage contains a progenitor cell population [J]. J Cell Sci, 2004, 117(Pt 6)∶889-897
[16] Pretzel D, Linss S, Rochler S, et al. Relative percentage and zonal distribution of mesenchymal progenitor cells in human osteoarthritic and normal cartilage [J]. Arthritis Res Ther, 2011, 13(2)∶R64
[17] Nathan J, Ruscitto A, Pylawka S, et al. Fibrocartilage stem cells engraft and self-organize into vascularized bone [J]. J Dent Res, 2017, 97(3)∶329-337
[18] Khan IM, Bishop JC, Gilbert S, et al. Clonal chondroprogenitors maintain telomerase activity and Sox9 expression during extended monolayer culture and retain chondrogenic potential [J]. Osteoarthritis Cartilage, 2009, 17(4)∶518-528
[19] Henson FM, Bowe EA, Davies ME. Promotion of the intrinsic damage-repair response in articular cartilage by fibroblastic growth factor-2 [J]. Osteoarthritis Cartilage, 2005, 13(6)∶537-544
[20] 周建新,杨晓斐,李阳,等.软骨前体细胞的分离鉴定及IL-1β对其成软骨分化的影响[J].中国修复重建外科杂志,2015,29(7)∶863-869
[21] Joos H, Wildner A, Hogrefe C, et al. Interleukin-1 beta and tumor necrosis factor alpha inhibit migration activity of chondrogenic progenitor cells from non-fibrillated osteoarthritic cartilage [J]. Arthritis Res Ther, 2013, 15(5)∶R119
[22] Jang KW, Ding L, Seol D, et al. Low-intensity pulsed ultrasound promotes chondrogenic progenitor cell migration via focal adhesion kinase pathway [J]. Ultrasound Med Biol, 2014, 40(6)∶1177-1186
[23] Seol D, Yu Y, Choe H, et al. Effect of short-term enzymatic treatment on cell migration and cartilage regeneration: in vitro organ culture of bovine articular cartilage [J]. Tissue engineering Part A, 2014, 20(13-14)∶1807-1814
[24] Levato R, Webb WR, Otto IA, et al. The bio in the ink: cartilage regeneration with bioprintable hydrogels and articular cartilage-derived progenitor cells [J]. Acta Biomater, 2017, 61∶41-53
[25] Yu Y, Brouillette MJ, Seol D, et al. Use of recombinant human stromal cell-derived factor 1alpha-loaded fibrin/hyaluronic acid hydrogel networks to achieve functional repair of full-thickness bovine articular cartilage via homing of chondrogenic progenitor cells [J]. Arthritis Rheumatol, 2015, 67(5)∶1274-1285
[26] Waller KA, Chin KE, Jay GD, et al. Intra-articular recombinant human proteoglycan 4 mitigates cartilage damage after destabilization of the medial meniscus in the Yucatan minipig [J]. Am J Sports Med, 2017, 45(7)∶1512-1521
[27] Caron MM, Emans PJ, Coolsen MM, et al. Redifferentiation of dedifferentiated human articular chondrocytes: comparison of 2D and 3D cultures [J]. Osteoarthritis Cartilage, 2012, 20(10)∶1170-1178
[28] Marcus P, De Bari C, Dell’Accio F, et al. Articular chondroprogenitor cells maintain chondrogenic potential but fail to form a functional matrix when implanted into muscles of SCID mice [J]. Cartilage, 2014, 5(4)∶231-240