Abstract: Objective: To study whether the nano-silver inorganic zirconium phosphate has antibacterial properties after being added to resin base by adhesion experiments in vitro. Methods: The nano-silver inorganic zirconium phosphate (Conval PAg-40) was added to the resin base at the ratio of 1%, 3%, 5%, and 7% to prepare resin specimens. The antimicrobial properties of all resin specimens against Streptococcus mutans, Actinomyces viscosus, Actinomyces naeslundii, Streptococcus sanguis, Porphynomoans gingivalis, and Candida albicans were tested by the film-sticking method after those specimens were milled and polished. The surface roughness values were measured by the roughness tester. Results: The colonies of Porphyromonas gingivalis cultured in groups of 3%, 5%, and 7%, and Streptococcus mutans, Actinomyces viscosus, Actinomyces naeslundii, Streptococcus sanguis, and Candida albicans cultured in groups of 1%, 3%, 5%, and 7% were lower than the control group (P<0.05). The antimicrobial rate of resin specimens gradually increased with the increase of addition. There was no significant difference in the number of Porphyromonas gingivalis colonies cultured in 1% group compared with that of the control group (P>0.05). Conclusion: The resin base with nano-silver inorganic zirconium phosphate has good antimicrobial activity, and its antimicrobial rate increases linearly with the proportion of antimicrobial agents.

Key words: denture resin base, nano-silver inorganic zirconium phosphate, antibacterial