Study on Effects of Butyric Acids on Periodontitis

doi:10.13701/j.cnki.kqyxyj.2020.04.003

Abstract

Abstract: Periodontitis is a chronic infectious disease of periodontal support tissue caused by plaque microorganisms. Plaque biofilm is the initiator of periodontitis. In recent years, periodontal pathogens metabolizing amino acids, hexose or anaerobic glycolysis, a metabolite produced by pentose, butyric acid, have attracted widespread attention. The development of butyric acid in periodontitis plays an important role. The butyric acid in the gingival crevicular fluid of patients with periodontitis was significantly higher than that of the healthy group. The high concentration of butyric acid in the oral cavity of periodontal patients may destroy the structure and function of periodontal tissue. This article reviews the effects of butyric acid on periodontitis.

Key words: butyric acid, periodontitis, cell cycle, cell death, inflammation

ZANG Wenli, LIU Junchao, PAN Yaping. Study on Effects of Butyric Acids on Periodontitis[J]. Journal of Oral Science Research, 2020, 36(4): 318-320.

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