Analysis of Regional Accelerated Phenomenon in Corticotomy-assisted Orthodontic Treatment by Micro CT

Abstract

Abstract: Objective: To observe the rate of tooth movement and the structure of alveolar bone in corticotomy-assisted orthodontic treatment by Micro-CT. Methods: 75 four or six-week male SD rats were used in this study. The rats were randomly divided into 3 groups:group1-CO+TM, group2-TM, group3-CO, with 5 in each one group. The rats were sacrificed at different times(t=4,7,14,21,28days). Micro-CT was used to measure the change of tooth movement and the structure of alveolar bone. Results: In terms of the amount of tooth movement, our results illustrated that the CO+TM group had a small amount at the beginning of the study compared with the TM group, CO+TM group was obvious higher than TM group from day 14 to 28(P<0.05). From day 4 to 7, TM was faster than CO+TM, then slower than CO+TM. When compared to CO and TM, CO+TM continued to drop at day 4,7,21,28. TM group went up at first and then went down. CO group was stable at 0(P<0.05). The bone volume in mesial of CO+TM group always decreased. As to TM group, the volume decreased in the early, but rebound after the 4th day. Conclusion: Alveolar bone corticotomy-assisted orthodontic treatment can accelerat the rate of tooth movement from day 14 to 28. There is a phenomenon called "regional accelerated phenomenon(RAP)" occured at day 21, It is associated with increased perfusion and bone turnover and decreased bone density.

Key words: AOO, Micro-CT, Bone volume, Boneminaral density, RAP

CLC Number:

R783.5

LIU Chang, LUAN Li-yang, JIANG Jiu-hui, et al. Analysis of Regional Accelerated Phenomenon in Corticotomy-assisted Orthodontic Treatment by Micro CT[J]. Journal of Oral Science Research, 2015, 31(7): 641-644.

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