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Research Progress of Emerging Strategy for Gingival Papillary Reconstruction TU Yuan, DING Yi 2024, 40(6): 473-478.  DOI: 10.13701/j.cnki.kqyxyj.2024.06.001 Abstract ( 125 )   PDF (1675KB) ( 103 )   Gingival papillary defect can produce black triangle, which leads to a series of problems such as aesthetic defects, pronunciation disorders, and food impaction, and even affects periodontal health. Therefore, gingival papillary reconstruction is important for oral aesthetics and function. However, tissue reconstruction of gingival papilla is one of the most difficult treatments in the aesthetic area due to the low blood supply and narrow location. By reviewing the literature, based on the theoretical basis of gingival papillary reconstruction, this paper mentions the current surgical methods and non-surgical treatment methods, and comprehensively summarizes emerging strategies based on laser, growth factor, cell, and scaffold, in order to provide certain references for the clinical treatment of gingival papillary reconstruction. References | Related Articles | Metrics

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Research Progress on Mouth Breathing and Oral Microecology in Children and Adolescents LI Mengru, WANG Xiaoqin 2024, 40(6): 479-483.  DOI: 10.13701/j.cnki.kqyxyj.2024.06.002 Abstract ( 81 )   PDF (816KB) ( 83 )   Mouth breathing, as a common problem in the growth and development of children and adolescents, has always been concerned by orthodontists. Long-term continuous chronic mouth breathing can cause abnormal growth of adolescents in the sagittal, horizontal and vertical directions. There will also have adverse changes in muscle function, including bite, cheek, and tongue muscle strength decline. In severe cases, systemic diseases can be induced. The accompanying 'adenoid and/or tonsil face' has attracted more and more attention from parents. With the launch of Human Microbiome Project in 2007, people began to pay attention to the correlation between oral microbiome changes and the occurrence and development of diseases. This article reviews the mouth breathing, oral microecology, and their correlation in children and adolescents. References | Related Articles | Metrics

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Advancements of Stem Cell Composites in Prevention and Treatment of Iatrogenic Osteonecrosis of the Jaw SHI Keying, ZHENG Yuanna 2024, 40(6): 484-488.  DOI: 10.13701/j.cnki.kqyxyj.2024.06.003 Abstract ( 67 )   PDF (835KB) ( 38 )   Medication-related osteonecrosis of the jaw (MRONJ) and osteoradionecrosis of the jaw (ORNJ) are two common and refractory iatrogenic osteonecrosis of the jaw, which pose significant clinical challenges. Given the swift progress in bone tissue engineering, the spotlight has shifted to stem cell composites comprised of biomaterials loaded with stem cells and their application in the prevention and treatment of MRONJ and ORNJ. This article reviews the pertinent researches on the prevention and treatment of MRONJ and ORNJ using stem cell composites. It elucidates the effects and influencing factors of stem cell composites in the context of preventing and treating MRONJ and ORNJ. Additionally, the article conducts an analysis of the unresolved issues within this technology, aiming to identify directions for future research endeavors and offering insights for clinical applications. References | Related Articles | Metrics

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Clinical and Periapical Healing Assessment of Autograft Teeth after Prophylactic Apical Closure CHEN Yue, CHI Junzhou, LIU Juanxiu, REN Xiaohua, TIAN Kun 2024, 40(6): 489-495.  DOI: 10.13701/j.cnki.kqyxyj.2024.06.004 Abstract ( 62 )   PDF (5390KB) ( 30 )   Objective: To evaluate the effect of apical surgery on autotransplantation teeth from three perspectives: clinic, image, and histology. Methods: Twenty-four teeth of three beagle dogs were randomly divided into a control group, an RCT group, and a Ref group (transplantation after root-end filling treatment). Clinical and image examinations were performed at 1, 4, and 12 weeks after surgery. Samples were subjected to micro CT scanning (calculated BV/TV, Tb. Sp, Tb.N, Tb.Th) and HE staining. Analytical statistics were performed to quantify loosening, PD values, and micro CT results. Results: Several teeth were lost in the three groups, and there was an improvement in the looseness at 12 weeks postoperatively. Mean loosening was significantly influenced by time and group (P<0.05). The decrease in PD values was significantly associated with time (P<0.05) and was significantly lower in the RCT and ref groups than that in the control group. In X-ray films, alveolar bone height was gradually decreased with bone remodeling, and some roots in the control group showed external resorption. The Tb. Sp in the RCT group was significantly lower than that in the control group (P<0.05). The Tb.N in the control group was significantly lower than those in the other two groups (P<0.05 and P<0.01). The apices of the Ref group were more closely related to the physiological structure and exhibited active bone repair confirmed by histology. Conclusion: Prophylactic apical sealing is effective in autograft teeth, which can simplify postoperative treatment and promote periodontal bone reconstruction of doner teeth. Accordingly, it is an effective modification of RCT for autografted teeth. References | Related Articles | Metrics

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Comparison of Er:YAG Laser, Resin Infiltrating, and Micro-grinding in Treatment of Enamel Demineralization CAO Xuanxuan, JIANG Dandan, WU Nan, ZHOU Zheng, DAI Haitao 2024, 40(6): 496-500.  DOI: 10.13701/j.cnki.kqyxyj.2024.06.005 Abstract ( 57 )   PDF (1369KB) ( 30 )   Objective: To compare and analyze the effects of Er:YAG laser, resin infiltration, and micro-grinding on tooth enamel demineralization. Methods: Forty-eight clinically extracted fresh premolars were collected and randomly divided into four groups after establishing artificial demineralization model. Group A was control group. Group B was micro-grinding group. Group C was permeable resin group. And group D was laser group. After 21 days, the four groups of isolated teeth were subjected to secondary demineralization. The microhardness and roughness of enamel surface was measured before treatment (t0), after demineralization (t1), after treatment (t2), and after secondary demineralization (t3). The treatment effect and surface structure of samples were observed by naked eyes and scanning electron microscope. Results: (1) At t0 and t1, there was no significant difference in enamel microhardness among four groups (P>0.05). At t2 and t3, the microhardness of group C was the largest, followed by group D and group B, and group A was the smallest. Except for group C and group D, there were significant differences among other groups (P<0.01). At t3, the microhardness of group A was lower than that at t1 (P<0.01), while those of groups B, C, and D were higher than that at t1 (P<0.01). (2) There was no significant difference in enamel surface roughness between groups at t0 and t1 (P>0.05). At t2 and t3, the roughness value of group C was the smallest, followed by group D and group B, and group A was the largest. There were significant differences among all groups (P<0.01). (3) Only the color of group C was basically normal observed by naked eye. (4) SEM observation showed that the surface voids of enamel in groups B, C, and D were significantly reduced compared with that in group A, and the smoothness was also improved. Conclusion: Resin infiltrated is superior to laser irradiation in improving the surface roughness of demineralized enamel, and obviously better than micro-grinding in improving the microhardness and anti-demineralization stability. References | Related Articles | Metrics

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Experimental Study on Regulation of Dnmt3b on Multidirectional Differentiation of Condylar Fibrocartilage Stem Cells YANG Hui, SU Jiansheng, ZHOU Yue 2024, 40(6): 501-505.  DOI: 10.13701/j.cnki.kqyxyj.2024.06.006 Abstract ( 51 )   PDF (8401KB) ( 39 )   Objective: To investigate the effect of DNA methyltransferase 3b enzyme (Dnmt3b) on adipogenic, osteogenic, and chondrogenic differentiation of rat condylar fibrocartilage stem cells (FCSCs). Methods: Rat condylar FCSCs were isolated and cultured in vitro. After using lentivirus to overexpress Dnmt3b in FCSCs, the cells were induced by adipogenesis, osteogenesis, and chondrogenesis. The expression of related genes to adipogenesis, osteogenesis, and chondrogenesis were detected. Results: Rat condylar FCSCs had the characteristics of mesenchymal stem cells. Compared with the control group, the expression of adipogenic gene peroxisome proliferator-activated receptorγ (Ppar-γ) in Dnmt3b overexpression group was decreased significantly, the expression of osteogenic gene Runt-related transcription factor 2 (Runx2) and alkaline phosphatase (ALP) was increased significantly, and the expression of chondrogenic gene SRY-related high mobility group-box gene 9 (Sox9) and aggrecan (ACAN) was increased significantly. Conclusion: Dnmt3b can promote chondrogenic and osteogenic differentiation of rat condylar FCSCs and inhibit their adipogenic differentiation. References | Related Articles | Metrics

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Changes of Resolvin D1 and Its Polarization Effect on Macrophages in Mandibular Distraction Osteogenesis Promoted by Parathyroid Hormone Administration LIU Yiheng, TIAN Liyue, LI Yongdi, YANG Zhishan, TANG Zhenglong 2024, 40(6): 506-511.  DOI: 10.13701/j.cnki.kqyxyj.2024.06.007 Abstract ( 40 )   PDF (2245KB) ( 10 )   Objective: To study the changes of Resolvin D1 (RvD1) and its effect on macrophage polarization during mandibular distraction osteogenesis promoted by parathyroid hormone (PTH). Methods: The mandibular distraction osteogenesis model was established in 48 rabbits and the rabbits were randomly divided into two groups. The experimental group was injected with PTH 20 μg/kg intermittently after operation, while the control group was injected with normal saline. Samples were taken on the 3rd, 5th, and 7th day of distraction, respectively, and the new bone tissue in the distraction area was observed by hematoxylin-eosin (HE) staining. LC-MS/MS was used to detect the content of RvD1 in the new bone tissue in the distraction zone. qPCR was used to detect the mRNA level of iNOS and Arg1 in new bone tissue. RAW264.7 cells were cultured and treated with LPS, RvD1, and LPS+RvD1, respectively. The expression level of macrophage polarization markers was detected by qPCR and flow cytometry. Results: HE staining and gross specimen observation showed that the new bone formation in the distraction zone of the experimental group was better than that of the control group. The content of RvD1 in the experimental group was significantly higher than that in the control group (P<0.01). qPCR results showed that PTH significantly increased the expression level of M2-type polarization marker Arg1 gene in macrophages, and decreased the expression level of M1-type polarization marker iNOS (P<0.01). In vitro, the expression level of Arg1 mRNA of M2-type polarization marker was up-regulated after RvD1 treatment, while the expression of iNOS mRNA of M1-type polarization marker was down-regulated(P＜0.01). The results of flow cytometry showed that the LPS-induced increase in CD86 expression was significantly reduced and CD206 expression was significantly elevated after treatment of cells with RvD1. Conclusion: Intermittent injection of PTH can increase the content of RvD1 in rabbit mandibular distraction osteogenesis. RvD1 can polarize macrophages to M2, thus exerting anti-inflammatory effects. References | Related Articles | Metrics

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Effect of Static Magnetic Field on Osteoblasts and Macrophages on Pure Titanium. JIANG Muqi, SUN Yuxuan, SUN Yasheng, NIE Zhixiang, ZHANG Zhen, HU Li 2024, 40(6): 512-518.  DOI: 10.13701/j.cnki.kqyxyj.2024.06.008 Abstract ( 42 )   PDF (4192KB) ( 12 )   Objective: To explore the effect and mechanism of static magnetic field on osteoblasts and macrophages on pure titanium surface. Methods: Under the static magnetic fields of 0 mT and 100 mT, cells were cultured on the surface of tissue culture well plates and sandblasting and acid etching (SLA-treated) titanium sheets, respectively. CCK-8 method was used to detect the effect of static magnetic field on the viability of osteoblasts and macrophages. Cytoskeleton fluorescence staining was used to detect the morphological changes of osteoblasts and macrophages under static magnetic field. Immunofluorescence staining was used to detect the expression of runt-related transcription factor 2 (Runx2), protein in osteoblasts under static magnetic field. The expression of osteogenesis-related genes in osteoblasts and immune-related genes in macrophages was detected by quantitative real-time fluorescence quantitative PCR (RT-qPCR). The expression levels of polarization-related proteins CD86 and CD206 in macrophages were detected by flow cytometry. Results: The static magnetic field of 100 mT could effectively promote the proliferation of osteoblasts on the titanium sheets, promote the expression of osteogenesis-related genes alkaline phosphatase (ALP), collagen type Ⅰ (COL-1), Runx2, and osteoprotegerin (OPG), and enhance the synthesis of osteogenesis-related protein Runx2. The static magnetic field of 100mT could promote the proliferation of macrophages, promote the polarization of macrophages to M1 type on the 3rd day, and inhibit the expression of inflammation-related genes tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) on the 7th day. Conclusion: Static magnetic field has the ability to promote the proliferation and mineralization of osteoblasts on the SLA-treated titanium sheets, and to promote the transformation of macrophages from pro-inflammatory to anti-inflammatory on the titanium sheets. References | Related Articles | Metrics

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Stress Distribution and Static Mechanical Analysis of 3D Printed Titanium Alloy Mandible Median Joint Fracture Plate WANG Huaisheng, LIU Rui, SONG Zhenyu, SONG Yihan, JIANG Tingting, HAN Zekui, SUN Guoshu, WANG Xinyu 2024, 40(6): 519-524.  DOI: 10.13701/j.cnki.kqyxyj.2024.06.009 Abstract ( 60 )   PDF (7271KB) ( 32 )   Objective: To analyze the stress distribution of titanium plate during the fixation process of mandible median combined fracture, and to evaluate the thickness, surface defects, surface roughness, and mechanical properties of 3D printed titanium plate. Methods: The shape of titanium plate used for finite element analysis and static mechanical analysis was digitally designed and modeled. Firstly, the middle joint fracture of mandible was simulated and fixed with titanium plate under unilateral biting force. Then, the thickness, roughness, and static mechanical properties of finished titanium plate and 3D printed titanium plate were tested. Results: By finite element analysis, the stress concentration of mandibular bone plate was mainly in the bridge part. The yield load and maximum load of 3D titanium plate were significantly greater than that of finished micro and small titanium plate. The thickness and roughness of the 3D printed titanium plate after grinding and polishing were close to that of the finished titanium plate. Conclusion: After 3D printed titanium plate is polished, its thickness parameters are accurate, and roughness and mechanical properties are better, which can meet clinical requirements. References | Related Articles | Metrics

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Application Research of Digital Fence Type Miniscrew Guide Plate Based on Chair Side Design and 3D Printing SONG Yi, ZHU Fangyong, XU Xiaohong, ZHOU Tao, ZHU Jialin, XU Yanhua, XU Haifeng, CAO Yannan 2024, 40(6): 525-529.  DOI: 10.13701/j.cnki.kqyxyj.2024.06.010 Abstract ( 48 )   PDF (3780KB) ( 31 )   Objective: To evaluate the application effect of digital fence type miniscrew guide plate manufactured by chair side design and 3D printing in implantation surgery of miniscrew. Methods: Fifteen patients who require miniscrew implantation were selected. Cone beam computed tomography (CBCT) of oral and maxillofacial regions was taken before surgery. Digital intraoral scanners were used to obtain oral scan images, and 3Shape Dental System software was used to fit the two images before designing a guide ring. The guide ring file and oral scan image were imported into Plasty CAD software to complete the design of the fence type guide plate. Chair side 3D printing equipment was used to print the guide plate. The plate was polished and trial worn after light curing. Thirty miniscrews were implanted under the guidance of the guide plate. Postoperative CBCT images were taken after surgery and aligned with preoperative CBCT images. The deviation, including angle deviation and position deviation, between the actual implantation and designed implantation was measured to analyze the accuracy. The minimum distance between the actual implanted miniscrew and the natural tooth root was measured to evaluate the safety of implantation. The fixation of miniscrews within 3 months after implantation was observed and the stability was evaluated. Results: The angle deviation between the actual implantation and the designed implantation of the miniscrews guided by the digital fence guide plate was (1.25±3.41)°, and the deviation values between the actual implantation and designed implantation of miniscrews in the neck and root positions were (0.17±0.46) mm and (0.13±0.41) mm, respectively. There was no statistically significant difference (P＞0.05). Thirty miniscrews did not contact with the root of the tooth, with safety level Ⅰ accounting for 86.67% and level Ⅱ accounting for 13.33%. There were no cases of level Ⅲ. Within 3 months after surgery, there was no loosening of the miniscrews, and the stability rate was 100%. Conclusion: The digital fence type miniscrew guide plate can effectively improve the accuracy, safety, and stability of implantation. The chair side design and 3D printing production method are convenient and reliable, which shortens the treatment cycle and has important application value. References | Related Articles | Metrics

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Effect of Gingival Biotype on Changes in Gingival Blood Flow under Orthodontic Forces Investigated by Laser Speckle Contrast Imaging YIN Fan, HAN Shuang, AN Qi, WANG Zhanli, GENG Rongguang, ZHAO Junwei 2024, 40(6): 530-536.  DOI: 10.13701/j.cnki.kqyxyj.2024.06.011 Abstract ( 45 )   PDF (2863KB) ( 9 )   Objective: To explore the effect of gingival biotype on gingival blood flow (BF) changes under orthodontic forces by laser speckle contrast imaging (LSCI). Methods: The study recruited a total of 24 subjects who met the inclusion criteria, with 12 individuals allocated to the thin gingival group and another 12 allocated to the thick gingival group. A force of 150 g was randomly applied between either the left or right maxillary canines and the first molar in each volunteer. Subsequently, dynamic monitoring of BF using LSCI was conducted at various time points: before force application, at 30 minutes, 1 day, 3 days, 7 days, and 14 days. Results: Through inter group comparison, there were significant differences in BF between the thin group and the thick group at various time points, with the BF of the thick group significantly higher than that of the thin group (P<0.05). After intra group comparison, there were significant differences in BF at each time point in each group (P<0.05). After applying force, local BF decreased to the minimum value within 30 minutes to 1 day, rose to the maximum value around 7 days, and basically returned to the baseline by 14 days. In a resting state without force loading, there was a significant difference in BF between the free gingiva and interdental papilla (P<0.05), and the BF of the free gingiva was significantly lower than that of the interdental papilla area. Conclusion: LSCI is a useful tool to real-time monitor gingival BF during orthodontic treatment. The BF of thin gingival type was significantly lower than that of thick gingival type. References | Related Articles | Metrics

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Effect of Orthodontic Movement of Maxillary First Molar on Zygomatic Pillar Remodeling LI Size, BAO Han, SU Xiaojie, GU Deao, MIAO Leiying, LIU Chao 2024, 40(6): 537-543.  DOI: 10.13701/j.cnki.kqyxyj.2024.06.012 Abstract ( 45 )   PDF (3594KB) ( 20 )   Objective: To study the effect of orthodontic movement of maxillary first molar on the structure of zygomatic pillar and the correlation between structural alteration and occlusal changes. Methods: Fifty patients with malocclusion (control group) and 50 patients receiving orthodontic treatment with extraction (experimental group) were selected, and the occlusal contact characteristics of two groups were analyzed with the Teetester,. Twenty-five patients with complete CBCT images were selected from the experimental group, and the CBCT images were analyzed with Mimics 21.0. The cross-sectional area of the zygomatic pillar, the movement of surface markers and the maxillary first molar, and the thickness and density of the alveolar bone and the cortical bone of the zygomatic pillar were measured. Results: The maxillary first molar showed changes in three-dimensional directions after orthodontic treatment, with significant mesial movement. The cross-sectional area of the lower section of the zygomatic pillar became smaller, the zygomatic point and the lowest point of the zygomaticomaxillary suture were displaced posteriorly, the thickness of the alveolar bone and the cortical bone decreased, and the above changes were correlated with the movement of the maxillary first molar. Total occlusal contact area (TCA), total occlusal force (TOF), and occlusal force of the maxillary first molar were reduced in the experimental group. Conclusion: Before and after orthodontic treatment with extraction, there was a correlation between the movement of maxillary first molar in three-dimensional directions and the modification of the structure of zygomatic pillar in the middle and lower segments. These alterations may affect the magnitude and the distribution of occlusal force. References | Related Articles | Metrics

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CBCT Study on Transverse Position of Mandibular First Molar with Different Vertical Facial Types LI Fang, ZHANG Xizhong 2024, 40(6): 544-549.  DOI: 10.13701/j.cnki.kqyxyj.2024.06.013 Abstract ( 44 )   PDF (1635KB) ( 9 )   Objective: To measure the physiological alveolar bone thickness of the mandibular first molar with different facial types using cone beam CT (CBCT) and evaluate the transverse position of the mandibular first molar. Methods: Fifty patients who had taken CBCT before orthodontics at the Second Department of Orthodontics, Hefei Stomatological Hospital from January 2023 to October 2023 were selected. They were divided into high angle group, mean angle group, and low angle group. The data were imported into the supporting 3D software to measure and analyze the thickness of alveolar bone at different depths in four locations. Results: The bone thickness of the first mandibular molar in high angle patients was the smallest. The lingual bone thickness of the first mandibular molar was higher than that of the buccal side. The thickness of the mesial lingual alveolar bone at the 4mm root of the mandibular first molar enamel cementum junction (CEJ) was higher than that of the distal lingual side, and there was no significant difference in the thickness of the mesial buccal alveolar bone compared to the distal buccal side. The thickness of the alveolar bone on the distal buccal side of the first mandibular molar at 8mm of the CEJ was higher than that on the mesiobuccal side, and there was no significant difference in the thickness of the alveolar bone on the mesiolingual side compared to the distal lingual side. The thickness of the alveolar bone below the CEJ of the first mandibular molar at the same measurement site, which was 8mm in the root, was higher than that of the alveolar bone at 4mm in the root. Conclusion: Different vertical facial types, measurement sites, measurement depths, and tooth anatomical shapes all reflect the differences in the transverse position of the mandibular first molar in the alveolar bone. References | Related Articles | Metrics

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Application of Mask-RCNN and Mimics in Maxillary Sinus Modeling WANG Rong, Pakezhati·SEYITI, WANG Tiemei, ZHANG Yi, QIAN Kun 2024, 40(6): 550-554.  DOI: 10.13701/j.cnki.kqyxyj.2024.06.014 Abstract ( 49 )   PDF (2124KB) ( 28 )   Objective: To compare the application of Mask RCNN deep learning model and Mimics 3D software in maxillary sinus modeling. Methods: Mask-RCNN and Mimics were applied to reconstruct the maxillary sinus and measure the volume of maxillary sinus from conical beam CT images in 50 patients included. The reconstruction effects of the two methods were compared, and the volume of the maxillary sinus was analyzed. Results: In the process of modeling the maxillary sinus, using Mask-RCNN for image segmentation, post-processing, and reconstruction only took more than 30 seconds, and using Mimics for manual threshold segmentation and reconstruction of maxillary sinus images for each patient took about tens of minutes. There was no significant difference in the volume of the maxillary sinus measured between two methods (P>0.05). Conclusion: The Mask RCNN deep learning algorithm is superior to Mimics and can reconstruct the maxillary sinus more quickly and accurately, reflecting the auxiliary diagnostic value of artificial intelligence in the field of oral and maxillofacial medical imaging. References | Related Articles | Metrics

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5-year Observation of Severe Periodontitis with Multidisciplinary Periodontal and Implant Treatment: A Case Report WEN Shang, GUO Jincai, ZHANG Minyi, YU Yulin, MA Fei, XIE Hui 2024, 40(6): 555-558.  DOI: 10.13701/j.cnki.kqyxyj.2024.06.015 Abstract ( 60 )   PDF (7604KB) ( 52 )   Stage Ⅳ and grade C periodontitis is the most severe type of periodontitis in the clinic. These patients are often accompanied by tooth loss and soft and hard tissue defects. It is necessary to design personalized plans through multidisciplinary treatment according to the patient's condition and progress. This paper reports the whole process of sequential treatment for a patient with stage Ⅳ and grade C periodontitis, including disease analysis, personalized design of treatment, multidisciplinary surgical procedure, supportive treatment, and 5-year follow-up observation. References | Related Articles | Metrics

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Removing of Fishbone in Root of Tongue Assisted by CBCT Localization: A Case Report ZHENG Xiaohong, FU Shuai, MA Wen, ZHANG Xin, WANG Lidong, LI Ming, WU Yong 2024, 40(6): 559-560.  DOI: 10.13701/j.cnki.kqyxyj.2024.06.016 Abstract ( 56 )   PDF (2024KB) ( 43 )   Oral foreign bodies are common in clinical treatment of oral and maxillofacial surgery. The most common places for foreign bodies were gums, tongue, bottom of mouth, and upper pharynx. However, foreign bodies in the root of tongue are rare and may cause a series of complications. The foreign body of fishbone in tongue base removed by CBCT-assisted localization was reported in this case. References | Related Articles | Metrics

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Possible for Immunoglobulin G4-related Disease with Lichenoid Lesion: A Case Report ZHANG Tianyu, LU Xuan, JIANG Lu 2024, 40(6): 561-563.  DOI: 10.13701/j.cnki.kqyxyj.2024.06.017 Abstract ( 44 )   PDF (3037KB) ( 20 )   Immunoglobulin G4 related disease (IgG4-RD) is a systemic multiorgan fibroinflammatory disease, rarely reported in cases involving oral mucosa. We report a patient with extensive lichenoid lesion. This report enriches the manifestations of oral mucosal lesions of IgG4-RD and suggests the importance of differential diagnosis in clinical practice. References | Related Articles | Metrics

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Psoriasis with Oral Lichenoid Lesions as Oral Manifestation: A Case Report LI Xinlei, LI Ting, ZHOU Gang 2024, 40(6): 564-567.  DOI: 10.13701/j.cnki.kqyxyj.2024.06.018 Abstract ( 46 )   PDF (3153KB) ( 22 )   Psoriasis is a chronic, inflammatory, systemic, immune-mediated disease induced by genetic and environmental interaction, mainly involving the skin and joints. Oral mucosal lesion in psoriasis is relatively rare. Existing studies have shown that the most common oral manifestations of psoriasis are non-specific manifestations such as geographic glossitis and fissured tongue. This manuscript reports the diagnosis and treatment of a case of psoriasis with oral lichenoid lesions as the oral manifestation, and explores its clinical features, as well as the diagnostic and treatment approaches. The aim of this case is to provide valuable insights for the clinical management of this disease. References | Related Articles | Metrics