牙周再生治疗研究进展

doi:10.13701/j.cnki.kqyxyj.2018.03.001

摘要/Abstract

摘要： 牙周炎导致牙周组织破坏,重建牙周组织的解剖结构和生理功能是研究者们努力的方向。然而,目前临床上尚难以实现真正意义上的牙周组织再生。牙周再生治疗需要安全有效的干细胞来源、充足的血液供应、稳定的再生空间以及在时间、空间上有序释放的多种生长因子等。多年来,学者们一直在寻找有效的治疗方法,并为此进行了大量研究。本文将从上述牙周再生中的关键问题切入,结合近年来的研究进展,探讨可能的解决方案。

关键词: 牙周再生治疗, 牙周组织工程, 牙周炎

Abstract: Periodontitis leads to the destruction of periodontal tissue. Reconstruction of the periodontal tissue with natural structure and the rehabilitation of its physiological function is the ultimate goal of the clinical treatment. Unfortunately, this has not yet been fully achieved in clinical practice. Currently, it is acknowledged that four aspects of periodontal tissue regeneration need to be improved. They are safe and effective stem cell sources, adequate blood supply, stable space for the regeneration process, and multiple growth factors that could be released in an ordered temporal and spatial manner. To achieve the above targets, different strategies have been challenged by many researchers. This paper aims to review the recent progress of periodontal tissue regeneration and try to find some prospective solutions which can guide future research directions of periodontal tissue regeneration.

Key words: Periodontal regenerative treatment, Periodontal tissue engineering, Periodontitis

闫福华, 李丽丽. 牙周再生治疗研究进展[J]. 口腔医学研究, 2018, 34(3): 217-222.

YAN Fu-hua, LI Li-li. Development in Periodontal Regenerative Treatment.[J]. Journal of Oral Science Research, 2018, 34(3): 217-222.

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