口腔医学研究 ›› 2021, Vol. 37 ›› Issue (6): 497-500.DOI: 10.13701/j.cnki.kqyxyj.2021.06.004

• 综述 • 上一篇    下一篇

炎症性肠病对牙周病影响的研究进展

林淑岚, 赵蕾*   

  1. 四川大学口腔疾病研究国家重点实验室,国家口腔疾病临床医学研究中心,四川大学华西口腔医院牙周病科 四川 成都 610041
  • 收稿日期:2020-04-30 出版日期:2021-06-28 发布日期:2021-06-17
  • 通讯作者: *赵蕾,E-mail: Jollyzldoc@163.com
  • 作者简介:林淑岚(1995~ ),女,福建福州人,住院医师,硕士,研究方向:牙周病学。
  • 基金资助:
    国家自然科学基金(编号:81970944)

Research Progress of Effect of Inflammatory Bowel Disease on Periodontal Disease

LIN Shulan, ZHAO Lei*   

  1. State Key Laboratory of Oral Diseases &
    National Clinical Research Center for Oral Diseases, Department of Periodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2020-04-30 Online:2021-06-28 Published:2021-06-17

摘要: 炎症性肠病(inflammatory bowel disease,IBD)是肠道的慢性炎症性疾病,除了典型的肠内表现外,患者还可伴有多种口腔表现,其中牙周病受到越来越多的关注。IBD与牙周病在发病机制上存在相似性,均与局部微生物及免疫稳态失衡有关。因此,本文就IBD对牙周病影响的证据及可能机制做一综述。

关键词: 炎症性肠病, 牙周病, 微生物, 免疫反应

Abstract: Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract. Except for predominant bowel symptoms, patients may also have oral manifestations, of which periodontal disease has gained increasing attention. The pathogeneses of IBD and periodontal disease can both be related to disturbance of local microbial and immune homeostasis. Therefore, the purpose of this paper is to summarize the evidences and possible mechanisms of the effect IBD may have on periodontal disease.

Key words: inflammatory bowel disease, periodontal disease, microbe, immune response