Journal of Oral Science Research ›› 2018, Vol. 34 ›› Issue (4): 356-358.DOI: 10.13701/j.cnki.kqyxyj.2018.04.005

Previous Articles     Next Articles

Research Progress on Anti-tumor Activity and Functionary Mechanism of Retinoic Acid

SUN Bin1,2, SUN Hong-chen2*   

  1. 1. Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Jilin University, Changchun 130021, China;
    2. Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Jilin University, Changchun 130021, China.
  • Received:2016-10-26 Online:2018-04-28 Published:2018-04-25

Abstract: In normal tissues, retinoic acid is involved in the regulation of differentiation of various tissue stem cells and plays an important role in human development. Moreover, it has been proved that retinoic acid can inhibit tumor growth and induce differentiation of tumor stem cells. The purpose of this review is to present the literature on the antitumor activity of retinoic acid and its mechanisms, which provides the basis for future research.

Key words: Retinoic acid, Functionary mechanism, Cancer