Research Progress on Regulation and Mechanism of microRNA on Dental Pulp Stem Cell Differentiation

doi:10.13701/j.cnki.kqyxyj.2021.02.005

Abstract

Abstract: Dental pulp stem cells are stem cells derived from neural crest with good self-renewal and multi-directional differentiation characteristics. They can differentiate into a variety of oral tissue related cells with low immunogenicity. It has been widely used as seed cells in tissue engineering and regenerative medicine fields. MicroRNA is a kind of short chain non-coding RNA that regulates the expression of target genes by acting on post-transcriptional RNA, which plays an important role in all aspects of life activities, such as cell growth, cell proliferation, embryonic development, tissue differentiation, and apoptosis. In this paper, we review the regulatory role and mechanism of microRNA in the differentiation of dental pulp stem cells.

Key words: microRNA, stem cells, differentiation

ZHAO Yun, MI Fanglin. Research Progress on Regulation and Mechanism of microRNA on Dental Pulp Stem Cell Differentiation[J]. Journal of Oral Science Research, 2021, 37(2): 113-117.

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