Clinicopathological Analysis of Primary Leiomyosarcoma of Parotid Gland

doi:10.13701/j.cnki.kqyxyj.2021.06.009

Abstract

Abstract: Objective: To investigate the clinicopathological features and differential diagnosis of primary leiomyosarcoma (LMS) of parotid gland. Methods: Two cases of primary parotid LMS were observed clinicopathologically and analyzed immunohistochemically, and the related literatures were reviewed. Results: Two male patients presented with parotid masses. Pathologic findings revealed that the sarcoma was composed of tumor cells arranged in a long spindle shape, parallel or interwoven bundles, and invaded the surrounding tissues. The immunohistochemical results showed that the tumor cells expressed SMA and Caldesmon. Two patients received surgery and radiotherapy and were followed up for two years without recurrence or distant metastasis. Conclusion: Primary parotid gland LMS was a rare malignant tumor in the maxillofacial region, which was difficult to be diagnosed preoperatively. Immunohistochemistry was helpful to the diagnosis of this disease.

Key words: parotid gland, leiomyosarcoma, immunohistochemistry

YU Fang, CHEN Qiongrong, XIANG Yuanhang, XU Jian. Clinicopathological Analysis of Primary Leiomyosarcoma of Parotid Gland[J]. Journal of Oral Science Research, 2021, 37(6): 519-522.

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