Effects of Standard Allicin on Enterococcus Faecalis Biofilms Control: an in vitro Study

Abstract

Abstract: Objective: To investigate the antibacterial efficacy of different concentrations dially trisulfide (DATS) on the biofilms of Enterococcus faecalis (E. faecalis) in vitro. Methods: E. faecalis was cultured in vitro to form the bacterial biofilm of different growth periods. Different concentrations of DATS, i.e. 1280μg/mL, 2560μg/mL and 5120μg/mL, were added to E. faecalis biofilms in different growth periods, and the bacteriostasis rates were measured by MTT method. Results: The bacteriostatic rates of 1280μg/mL DATS were about 71% in logarithmic phase and hunger phase, which were significantly higher than that in stability phase with bacteriostasis rate of 58% (P<0.05). DATS in concentration of 2560μg/mL and 5120μg/mL showed better antibacterial efficacy than that of 1280μg/mL, indicating that the antibacterial efficacy of DATS was in a concentration-dependent manner (P<0.05). Conclusion: DATS played a role in suppressing E. faecalis in the biofilm in vitro.

Key words: Allic, Enterococcus faecalis, Bacterial biofilm

CLC Number:

R780.1

WANG Xiang-zhu, XIE Xiao-li, CHEN Min-min, FENG Hai-yan. Effects of Standard Allicin on Enterococcus Faecalis Biofilms Control: an in vitro Study[J]. Journal of Oral Science Research, 2015, 31(9): 867-870.

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