Journal of Oral Science Research

Journal of Oral Science Research ›› 2018, Vol. 34 ›› Issue (11): 1196-1199.DOI: 10.13701/j.cnki.kqyxyj.2018.11.012

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Control Effect of Preimplantation Periodontitis in Elderly Patients with Moderate to Severe Periodontitis and Type 2 Diabetes Mellitus

SU Zhe-jun1*, WANG Peng1, HUO Feng1, LI Yi-ping2, CHEN Xue1, MA Li1   

  1. 1. Department of Stomatology, Affiliated Hospital of Chengde Medical College, Chengde 067000, China;
    2. Xiangya School of Stomatology, Zhongnan University, Changsha 410078, China
  • Received:2018-05-11 Online:2018-11-28 Published:2018-11-23

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Abstract: Objective: To investigate the effect of periodontal initial therapy on periodontal infection control, the changes in the level of MMP -8 in whole saliva and its clinical significance in elderly patients with moderate to advanced periodontitis with type2diabetes. Methods: 22 cases of elderly patients with moderate to severe periodontitis with type 2 diabetes were included in the experimental group, and 18 of the elderly patients with moderate and severe periodontitis were treated as the control group, and the whole periodontitis was treated with periodontal initial therapy. The clinical periodontal index and MMP-8 content in the whole saliva of two groups were detected before and 3 months after the periodontal initial therapy. Results: There was no significant difference in the levels of PD, PD>5 mm, BOP, and MMP-8 between two groups before therapy (P>0.05). The PD, PD>5 mm, BOP, and MMP-8 levels of two groups were significantly lower than those of baseline at 3 months after therapy, and the difference was statistically significant (P<0.05). There was no significant difference in the PD, PD>5 mm, and BOP between two groups (P>0.05), and the level of MMP-8 in the experimental group was not significantly lower than that in the control group (P<0.05). After 3 months of periodontal initial therapy, the PLI was less than 20%, the complete BOP was 22.7%, and the PD>5 mm was 13.6% in the experimental group. Conclusion: Simple periodontal initial therapy can improve the periodontal clinical indexes of elderly patients with moderate to advanced periodontitis with type 2 diabetes, and reduce the level of MMP-8 in the whole saliva. Periodontal infection control is satisfactory. Compared with elderly patients with moderate to advanced periodontitis, the effect of inflammatory therapy is poor after periodontal initial therapy in elderly patients with mo- derate to advanced periodontitis and type 2 diabetes.

Key words: Type 2 diabetes mellitus, Chronic periodontitis, Periodontal initial therapy, Matrix metalloproteinase-8