Regulatory Effects and Molecular Mechanisms of Irisin on Periodontal Tissue Repair and Regeneration

doi:10.13701/j.cnki.kqyxyj.2025.05.002

Abstract

Abstract: Irisin is a polypeptide hormone with a promising role in reducing the inflammatory response of metabolic syndrome and treating bone metabolism-related diseases. We reviewed the anti-inflammatory capacity of irisin and its influence on bone metabolism. What’s more, the regulatory effects and molecular mechanisms of irisin on periodontal tissue repair and regeneration were investigated, in order to explore the potential role of irisin as a novel immunological agent for the treatment of periodontal inflammatory bone defects.

Key words: irisin, anti-inflammatory, bone metabolism, periodontal tissue regeneration, immunological agents

YANG Yuxin, MA Qian. Regulatory Effects and Molecular Mechanisms of Irisin on Periodontal Tissue Repair and Regeneration[J]. Journal of Oral Science Research, 2025, 41(5): 369-372.

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